Solid-state NMR spectroscopy on complex biomolecules [PDF]
, 2010 Biomolecular applications of NMR spectroscopy are often merely associated with soluble molecules or magnetic resonance imaging. However, since the late 1970s, solid-state NMR (ssNMR) spectroscopy has demonstrated its ability to provide atomic-level ...
NMR Spectroscopy +7 more
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Binding hotspots of BAZ2B bromodomain:histone interaction revealed by solution NMR driven docking [PDF]
, 2014 Bromodomains are epigenetic reader domains, which have come under increasing scrutiny both from academic and pharmaceutical research groups. Effective targeting of the BAZ2B bromodomain by small molecule inhibitors has been recently reported, but no ...
Ferguson, Fleur M. +26 more
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CASD-NMR: critical assessment of automated structure determination by NMR [PDF]
, 2009 NMR spectroscopy is currently the only technique for determining the solution structure of biological macromolecules. This typically requires both the assignment of resonances and a labor-intensive analysis of multidimensional nuclear Overhauser effect ...
NMR Spectroscopy +4 more
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Nuclear magnetic resonance (NMR) applied to membrane-protein complexes [PDF]
, 2016 Increasing evidence suggests that most proteins occur and function in complexes rather than as isolated entities when embedded in cellular membranes.
Baldus, Marc +5 more
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Proton magnetic resonance studies of the aggregation of taurine-conjugated bile salts.
Journal of Lipid Research, 1992 The concentration dependence of the 500 MHz 1H-NMR spectra of taurocholate, taurochenodeoxycholate, taurodeoxycholate, and the monosulfate esters of taurochenodeoxycholate has been examined at 0.154 M NaCl in D2O.
RD Stevens +3 more
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Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR
Nature Communications, 2018 The β-barrel assembly machinery (BAM) catalyzes β-barrel protein insertion into the outer membrane of E.coli. Here authors employ high-sensitivity solid-state NMR to reveal how the lipid environment and formation of the BamA-BamCDE complex affect BamA ...
Cecilia Pinto +5 more
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A NMR guided approach for CsrA–RNA crystallization [PDF]
, 2013 Structure determination of protein–nucleic acid complexes remains a challenging task. Here we present a simple method for generating crystals of a CsrA–nucleic acid complex, guided entirely by results from nuclear magnetic resonances spectroscopy (NMR ...
NMR Spectroscopy +5 more
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Chemical shift extremum of 129Xe(aq) reveals details of hydrophobic solvation
Scientific Reports, 2018 The 129Xe chemical shift in an aqueous solution exhibits a non-monotonic temperature dependence, featuring a maximum at 311 K. This is in contrast to most liquids, where the monotonic decrease of the shift follows that of liquid density.
Petri Peuravaara +5 more
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Development of Genistein Synthesis for Use as a Certified Reference Material
Разработка и регистрация лекарственных средств, 2021 Introduction. The use of certified reference materials (CRMs) ensures metrological traceability and comparability of analysis results performed in different laboratories, by different analysts, at different times.
A. A. Zhigalina +3 more
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Hydration dynamics of the collagen triple helix by NMR [PDF]
, 2000 The hydration of the collagen-like Ac-(Gly-Pro-Hyp)(6)-NH2 triple-helical peptide in solution was investigated using an integrated set of high-resolution NMR hydration experiments, including different recently developed exchange-network editing methods ...
Kaptein, R +6 more
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