Results 21 to 30 of about 887,442 (314)

Structural characterization of intrinsically disordered proteins by NMR spectroscopy. [PDF]

, 2013
Recent advances in NMR methodology and techniques allow the structural investigation of biomolecules of increasing size with atomic resolution. NMR spectroscopy is especially well-suited for the study of intrinsically disordered proteins (IDPs) and ...
Contreras-Martos, Sara, Peter Tompa, Cedeno, Cesyen, Simone Kosol, Kosol, Simone, Tompa, Péter, Sara Contreras-Martos, Cesyen Cedeño   +7 more
core   +1 more source

Synthesis and Characterization of Mannich base Derivative from benzotriazole [PDF]

Kirkuk Journal of Science, 2016
This study include prepared number of new Mannich bases derived from equivalent moles p-hydroxybenzaldehyde with equivalent moles from benzotriazole and primary amines in the ethanol as a solvent.
Fariq Salah Ahmed, Khalid M. Mohammed, Ayad S. Hameed   +2 more
doaj   +1 more source

Consoramides A–C, New Zwitterionic Alkaloids from the Fungus Irpex consors

Mycobiology, 2021
In our ongoing search for new secondary metabolites from fungi, a basidiomycete fungus Irpex consors was selected for mycochemical investigation, and three new zwitterionic alkaloids (1-3) and five known compounds (4-8) were isolated from the culture ...
Ji-Yul Kim, Dae-Won Ki, Yoon-Ju Lee, Lee Su Ha, E-Eum Woo, In-Kyoung Lee, Bong-Sik Yun   +6 more
doaj   +1 more source

Exploiting periodic first-principles calculations in NMR spectroscopy of disordered solids [PDF]

, 2013
Much of the information contained within solid-state nuclear magnetic resonance (NMR) spectra remains unexploited because of the challenges in obtaining high-resolution spectra and the difficulty in assigning those spectra.
Ashbrook, Sharon Elizabeth, Dawson, Daniel McLean, Ashbrook, Sharon Elizabeth ; id_orcid, Dawson, Daniel McLean; id_orcid   +3 more
core   +1 more source

An inter-laboratory comparison demonstrates that [H-1]-NMR metabolite fingerprinting is a robust technique for collaborative plant metabolomic data collection. [PDF]

, 2010
In any metabolomics experiment, robustness and reproducibility of data collection is of vital importance. These become more important in collaborative studies where data is to be collected on multiple instruments.
Biais, Benoit, Beale, Michael H., Sofia Moco, Jacques Vervoort, Maucourt, Mickael,, Ward, J.L., Michael H. Beale, Lommen, Arjen, Rolin, D., Maucourt, Mickael, M., Moco, Sofia, Vervoort, J., Baker, J. M., Humpfer, Eberhard, Deborde, C., Beale, M.H., Ward, J. L., Deborde, Catherine,, Maucourt, M., Mickael Maucourt, Beale, M. H., Annick Moing, Lommen, A., Jane L. Ward, Vervoort, J.J.M., Hartmut Schäfer, Schäfer, Hartmut, Deborde, Catherine, Baker, J.M., Arjen Lommen, Miller, S.J., Vervoort, Jacques, Eberhard Humpfer, Miller, Sonia J., Rolin, Dominique, D., Moco, S.I.A., Rolin, Dominique,, John M. Baker, Baker, John M., Benoit Biais, Catherine Deborde, Moco, S., Ward, Jane L., Biais, B., Dominique Rolin, Moing, Annick, Humpfer, E., Moing, A., Miller, S. J., Sonia J. Miller, Schafer, H., Maucourt, Mickael, Beale, Mike, Rolin, Dominique, Ward, Jane   +54 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

New methods and applications in solid-state NMR spectroscopy of quadrupolar nuclei [PDF]

, 2014
The authors acknowledge the EPSRC for the award of a studentship to S.S. Accepted Oct 8th 2014Solid-state nuclear magnetic resonance (NMR) spectroscopy has long been established as offering unique atomic-scale and element-specific insight into the ...
Ashbrook, Sharon E, Sneddon, Scott, Ashbrook, Sharon E; id_orcid   +2 more
core   +1 more source

A new structural arrangement in proteins involving lysine NH3 + group and carbonyl

Scientific Reports, 2017
Screening of the Protein Data Bank led to identification of a recurring structural motif where lysine NH3 + group interacts with backbone carbonyl. This interaction is characterized by linear atom arrangement, with carbonyl O atom positioned on the three-
Olga N. Rogacheva, Sergei A. Izmailov, Lyudmila V. Slipchenko, Nikolai R. Skrynnikov   +3 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Protein folding on the ribosome studied using NMR spectroscopy [PDF]

, 2013
NMR spectroscopy is a powerful tool for the investigation of protein folding and misfolding, providing a characterization of molecular structure, dynamics and exchange processes, across a very wide range of timescales and with near atomic resolution.
Christodoulou, J, Christodoulou, John, Launay, H, Cabrita, L.D., Launay, H., Waudby, CA, Cabrita, LD, Waudby, Christopher A.   +7 more
core   +1 more source