Results 121 to 130 of about 14,257 (250)

Next-Generation Sequencing Reveals a High Frequency of HIV-1 Minority Variants and an Expanded Drug Resistance Profile among Individuals on First-Line ART

Viruses
We assessed the performance and clinical relevance of Illumina MiSeq next-generation sequencing (NGS) for HIV-1 genotyping compared with Sanger sequencing (SS).
Maria Nannyonjo, Jonah Omooja, Daniel Lule Bugembe, Nicholas Bbosa, Sandra Lunkuse, Stella Esther Nabirye, Faridah Nassolo, Hamidah Namagembe, Andrew Abaasa, Anne Kazibwe, Pontiano Kaleebu, Deogratius Ssemwanga   +11 more
doaj   +1 more source

HIV versus the Terminator: Drug resistance of HIV reverse transcriptase with mutations at the connection subdomain [PDF]

, 2008
only availableAntiretroviral drug therapy can prolong the life of an HIV-infected individual, but this treatment also promotes drug-resistance mutations.
Jackson, Jacob C., Sarafianos, Stefan G., Schuckmann, Matthew M.   +2 more
core  

Patterns of emergent resistance-associated mutations after initiation of non-nucleoside reverse-transcriptase inhibitor-containing antiretroviral regimens in Taiwan: a multicenter cohort study

Infection and Drug Resistance, 2018
Chien-Yu Cheng,1,2 Mao-Song Tsai,3 Chia-Jui Yang,3,4 Shu-Hsing Cheng,1,5 Hsin-Yun Sun,6 Shu-Fang Chang,7 Li-Hsin Su,7 Yi-Ching Su,6 Chien-Ching Hung,6,8–10 Sui-Yuan Chang7,11 For the Taiwan HIV Study Group 1Department of Internal Medicine, Taoyuan ...
Cheng CY, Tsai MS, Yang CJ, Cheng SH, Sun HY, Chang SF, Su LH, Su YC, Hung CC, Chang SY   +9 more
doaj  

Survival, plasma HIV-1 RNA concentrations and drug resistance in HIV-1-infected Haitian adolescents and young adults on antiretrovirals

Bulletin of the World Health Organization
OBJECTIVE: To assess outcomes after antiretroviral therapy (ART) in adolescents and youth in Haiti, a country with a generalized epidemic of infection with HIV-1.
Macarthur Charles, Francine Noel, Paul Leger, Patrice Severe, Cynthia Riviere, Carole Anne Beauharnais, Erica Miller, John Rutledge, Heejung Bang, Wesley Shealey, Richard T D'Aquila, Roy M Gulick, Warren D Johnson Jr, Peter F Wright, Jean William Pape, Daniel W Fitzgerald   +15 more
doaj   +1 more source

Multiple dosage forms of the NNRTI microbicide dapivirine: product development and evaluation [PDF]

, 2006
Joseph Romano
openalex   +1 more source

Dual therapy with Atazanavir/ritonavir plus Raltegravir versus triple therapy with Atazanavir/ritonavir plus Tenofovir-Emtricitabine after failure to an NNRTI regimen: 48-week results of the randomized pilot study ARTE trial [PDF]

, 2022
María Inés Figueroa, Omar Sued, Carina César, Patricia Patterson, Cleyton Yamamoto, Valeria Fink, Norma Luna, Antonio Camiro-Zúñiga, Ana Gun, Pedro Cahn   +9 more
openalex   +1 more source

HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola

Scientific Reports
The surveillance of drug resistance in the HIV-1 naïve population remains critical to optimizing the effectiveness of antiretroviral therapy (ART), mainly in the era of integrase strand transfer inhibitor (INSTI) regimens.
Cruz S. Sebastião, Ana B. Abecasis, Domingos Jandondo, Joana M. K. Sebastião, João Vigário, Felícia Comandante, Marta Pingarilho, Bárbara Pocongo, Edson Cassinela, Fátima Gonçalves, Perpétua Gomes, Marta Giovanetti, Ngiambudulu M. Francisco, Euclides Sacomboio, Miguel Brito, Jocelyne Neto de Vasconcelos, Joana Morais, Victor Pimentel   +17 more
doaj   +1 more source

Connection subdomain mutations in HIV-1 subtype-C treatment-experienced patients enhance NRTI and NNRTI drug resistance

, 2012
Krista A. Delviks‐Frankenberry, Renan B. Lengruber, André F. Santos, Jussara Silveira, Marcelo A. Soares, Mary F. Kearney, Frank Maldarelli, Vinay K. Pathak   +7 more
openalex   +2 more sources

Computational modelling, green synthesis and biological activity of arylsulfonilamides as NNRTIs against HIV-1 [PDF]

, 2014
Anuradha Singh, Madhu Yadav, Nidhi Singh, Ritika Srivastava, Rajinder Kaur, Gupta Sk, Ramendra K. Singh   +6 more
openalex   +1 more source

Structure-and Privileged Fragment-Based IterativeOptimization: Discovery of 2,4-Disubstituted-6-aminopyrimidines asNovel HIV‑1 NNRTIs with Potent Activity against Drug-ResistantStrains and Favorable Safety Profiles

Xiangkai Ji (22263386), Xiangyi Jiang (6378059), Heng Gao (619751), Zhen Gao (609801), Erik De Clercq (7541327), Christophe Pannecouque (496139), Dongwei Kang (3080175), Peng Zhan (433925), Xinyong Liu (1730737)   +8 more
  +4 more sources