Results 111 to 120 of about 3,155,563 (287)

No-Observed-Adverse-Effect Level (NOAEL)

, 2016
John H. Duffus, Monica Nordberg, Douglas M. Templeton   +2 more
core   +5 more sources

Effects of in utero and lactational exposure to the no-observed-adverse-effect level (NOAEL) dose of the neonicotinoid clothianidin on the reproductive organs of female mice. [PDF]

J Vet Med Sci, 2021
Kitauchi S, Maeda M, Hirano T, Ikenaka Y, Nishi M, Shoda A, Murata M, Mantani Y, Yokoyama T, Tabuchi Y, Hoshi N.   +10 more
europepmc   +1 more source

Adverse Selection and Non-Exclusive Contracts [PDF]

This paper studies the Rothschild and Stiglitz (1976) adverse selection environment, relaxing the assumption of exclusivity of insurance contracts. Agents can engage in multiple insurance contracts simultaneously, and the terms of these contracts are not
Pricila Maziero, Laurence Ales
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Adverse Selection and the Challenges to Stand-Alone Prescription Drug Insurance [PDF]

This paper investigates a possible predictor of adverse selection problems in unsubsidized stand-alone' prescription drug insurance: the persistence of an individual's high spending over multiple years.
Mark V. Pauly, Yuhui Zeng
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Lyophilized B. subtilis ZB183 Spores: 90-Day Repeat Dose Oral (Gavage) Toxicity Study in Wistar Rats

Journal of Toxicology, 2019
A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on lyophilized spores of the novel genetically modified strain B. subtilis ZB183.
B. Appala Naidu, Kamala Kannan, D. P. Santhosh Kumar, John W. K. Oliver, Zachary D. Abbott   +4 more
doaj   +1 more source

Fetal and lactational exposure to the no-observed-adverse-effect level (NOAEL) dose of the neonicotinoid pesticide clothianidin inhibits neurogenesis and induces different behavioral abnormalities at the developmental stages in male mice. [PDF]

J Vet Med Sci, 2021
Maeda M, Kitauchi S, Hirano T, Ikenaka Y, Nishi M, Shoda A, Murata M, Mantani Y, Tabuchi Y, Yokoyama T, Hoshi N.   +10 more
europepmc   +1 more source

Regulation of private health insurance markets: Lessons from enrollment, plan type choice, and adverse selection in Medicare Part D [PDF]

We study the Medicare Part D prescription drug insurance program as a bellwether for designs of private, non-mandatory health insurance markets that control adverse selection and assure adequate access and coverage.
Daniel McFadden, Florian Heiss, Joachim Winter   +2 more
core  

Individual-level and community-level effect modifiers of the temperature-mortality relationship in 66 Chinese communities

, 2015
Objectives \ud \ud - To examine the modification of temperature-mortality association by factors at the individual and community levels.\ud \ud Design and methods \ud \ud - This study investigated this issue using a national database comprising daily ...
Xiao, Jianpeng, Lin, Hualiang, Tong, Shilu, Huang, Zhengjing, Liu, Yunning, Ebi, Kristie, Li, Xing, Ma, Wenjun, Wang, Lijun, Zeng, Weilin, Zhou, Mai-Geng, Liu, Tao, Zhang, Yonghui   +12 more
core   +1 more source