Results 131 to 140 of about 3,161,134 (287)

The level of observed physical movement accompanying periodic limb movements measured in a clinical sleep population [PDF]

open access: yes, 2018
Robert G Hooper The Sleep Center, Scottsdale, AZ, USA Study objectives: Periodic limb movements (PLMs) are routinely measured during polysomnogram (PSG) testing.
Hooper RG
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Clinical observation of responses to two plasma concentrations of tacrolimus in treatment of idiopathic membranous nephropathy stage Ⅱ

open access: yesLinchuang shenzangbing zazhi, 2019
Objective To observe the clinical responses to two plasma concentrations of tacrolimus in treatment of idiopathic membranous nephropathy stageⅡ. Methods A total of 90 patients diagnosed with idiopathic membranous nephropathy stageⅡ through renal puncture
LI Xiao-yong
doaj  

Oral reference dose (RfD) derivation for five bisphenol A alternatives integrating BMD and NOAEL/LOAEL approaches

open access: yesEcotoxicology and Environmental Safety
Bisphenols (BPs) are widely used in plastic manufacturing, food packaging, and other industrial applications, with bisphenol A (BPA) being one of the most extensively produced chemicals globally.
Yan Xia   +5 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Tax incentives for private life annuities and the social security reform: Effects on consumption and on adverse selection [PDF]

open access: yes
In this paper we analyse several measures which are typically included in a social security reform: a cut in the social security benefits, an increase in the social security tax and tax incentives for the purchase of private life annuities, which have ...
Susanne Pech
core  

Requirements for occupational exposure limits in psychosocial risk assessment: What we know, what we don’t know and what we can learn from other disciplines

open access: yesScandinavian Journal of Work, Environment & Health
OBJECTIVES: This discussion paper aims to provide recommendations for the development of occupational exposure limits (OEL) for psychosocial hazards.
Roman Pauli   +5 more
doaj   +1 more source

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