Results 221 to 230 of about 921,415 (254)

A new approach to deriving community exposure guidelines from “no-observed-adverse-effect levels”

Regulatory Toxicology and Pharmacology, 1990
The world community desires accurate and reliable information about possible health hazards from exposure to chemicals in the environment. For example, Title III of the Superfund Amendments and Reauthorization Act (SARA, U.S. Congress, 1986) requires plant operators to disclose data on air, water, and waste emissions for over 300 chemicals.
S C, Lewis, J R, Lynch, A I, Nikiforov
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Confirmation of an acute no-observed-adverse-effect and low-observed-adverse-effect level for copper in bottled drinking water in a multi-site international study

Regulatory Toxicology and Pharmacology, 2003
In a double blind, 3x3 factorial (volumexdose) study, 70 adult females (18-60 years of age) at four different international sites (total pooled n=269) were given 100, 150, or 200ml of bottled drinking water with 0.4, 0.8, or 1.2mg of copper (Cu) as the sulfate salt once each week.
Araya, Magdalena, Chen, Bingheng, Klevay, Leslie M., Strain, J. J., Johnson, Luann, Robson, Paula, Shi, Wei, Nielsen, Forrest, Zhu, Huigang, Olivares Grohnert, Manuel, Pizarro Aguirre, Fernando, Haber, Lynne T.   +11 more
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An updated evaluation of reported no-observed adverse effect levels for chrysotile asbestos for lung cancer and mesothelioma

Critical Reviews in Toxicology, 2016
Although consumption of chrysotile asbestos has decreased since the 1970s, the latency period of asbestos-related cancers is thought to be at least 20-30 years, and therefore the potential health risks associated with historical exposures is still actively researched.
Jennifer S, Pierce, Peter S, Ruestow, Brent L, Finley   +2 more
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Determination of no-observed-adverse-effect levels and eliciting doses in a representative group of peanut-sensitized children

Journal of Allergy and Clinical Immunology, 2006
Current labeling practices for allergenic foods like peanut can be inadequate. For future regulatory and industry guidelines, information on no-observed-adverse-effect levels (NOAELs) and eliciting doses (EDs) for allergenic foods is necessary.To determine NOAEL and ED in a representative group of peanut-sensitized children, relate these data to ...
Annebeth E, Flinterman, Suzanne G, Pasmans, Maarten O, Hoekstra, Yolanda, Meijer, Els, van Hoffen, Edward F, Knol, Susan L, Hefle, Carla A, Bruijnzeel-Koomen, André C, Knulst   +8 more
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Low‐level exposure of guinea pigs and marmosets to sarin vapour in air: lowest‐observable‐adverse‐effect level (LOAEL) for miosis

Journal of Applied Toxicology, 2004
AbstractThe purpose of this pilot study was to indicate, for low‐level exposure of conscious guinea pigs and marmoset monkeys to sarin vapour in air, the lowest‐observable‐adverse‐effect level (LOAEL) of sarin for miosis. This is the concentration × time (C·t) value (t = 5 h) of exposure at which miosis becomes significant.The ratio of pupil and iris ...
Helden, H.P.M. van, Trap, H.C., Kuijpers, W.C., Oostdijk, J.P., Benschop, H.P., Langenberg, J.P.   +5 more
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[Study of No Observed Adverse Effect Level of Nickel and Its Preliminary Evaluation Biocompatibility].

Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation, 2020
The purpose of this study was to investigate the NOAEL of the nickel ion and provide with basic data for the biological evaluation of those medical devices containing nickel. Five groups SD rats were repeatedly exposed during 14 d respectively to nickel at first stage doses of 4.9, 3.7, 2.5 mg/(kg.d), and the second stage doses of 1.2, 0.25 mg/(kg.d ...
Xueying, He, Juli, Tang, Xiantao, Wen, Bo, Guan, Rui, Wang, Hui, Wang, Hua, Li, Jianfeng, Shi, Yali, Zeng, Yongjian, Mao   +9 more
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Comparison of benchmark doses (BMD) with no-observed-adverse-effect-levels (NOAELs) and low-observed-adverse-effect-levels (LOAELs) for subchronic toxicity studies

Toxicology Letters, 1994
R.S. Nair, M.A. Martens
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Moving towards personalized treatments of immune-related adverse events

Nature Reviews Clinical Oncology, 2020
Marie Hudson, Bertrand Routy, Leonard Calabrese   +2 more
exaly  

No Observable Adverse Effect Level (NoAEL)

2011
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No Observable Adverse Effect Level (NoAEL)

2006
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