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Generalisation of Placebo and Nocebo Effects: Current Knowledge and Future Directions

European Journal of Pain
Placebo and nocebo effects are beneficial or adverse treatment outcomes upon administration of inert treatment components. These effects have been frequently studied on pain.
Lingling Weng   +3 more
semanticscholar   +1 more source

Placebo and nocebo effects.

Pain
We introduce the Psychoneurobiology, Individualization, and Normalization (PIN) framework of placebo and nocebo effects. Traditionally, research primarily focused on psychoneurobiological mechanisms of these effects, the Psychoneurobiology phase ...
Belina Rodrigues   +8 more
semanticscholar   +1 more source

Forebrain networks driving brainstem pain modulatory circuits during nocebo hyperalgesia in healthy humans

Pain
The forebrain circuits that regulate pain modulatory circuits during hyperalgesia are unknown. We identify forebrain activity and forebrain-brainstem connectivity that underpins nocebo hyperalgesia.
L. Crawford   +7 more
semanticscholar   +1 more source

Evidence Distortion and Clinical Decision-Making: How Placebo and Nocebo Effects Mediate Industry Influence in Prescribing Practices

Journal of Behavioral Health and Psychology
This paper examines the complex interplay between placebo and nocebo effects in pharmaceutical treatments and how these psychobiological phenomena are leveraged or obscured through pharmaceutical industry influence.
Julian Ungar-Sargon
semanticscholar   +1 more source

Comparing the effects of message framing and nocebo education on psychological outcomes.

Annals of Behavioral Medicine
BACKGROUND Nocebo effects from side effect disclosure are an unfortunate yet common occurrence in health care. Two prominent methods proposed for reducing nocebo effects from side effect disclosure are positive framing and nocebo education. PURPOSE The
Emily K. Spotts   +2 more
semanticscholar   +1 more source

Icelandic physiotherapists’ perceptions of contextual factors as triggers of nocebo effects: a mixed methods survey

Physiotherapy Theory and Practice
Introduction Contextual factors surrounding physiotherapy treatment can trigger nocebo effects, resulting in negative outcomes despite evidence-based treatment. Purpose This study explored Icelandic physiotherapists’ awareness, perception, and prevention
A. Snook   +5 more
semanticscholar   +1 more source

Placebo and nocebo effect in pain

Handbook of Clinical Neurology
Understanding the mechanisms of pain modulation is pivotal for elucidating the role of the placebo effect in pain management. This chapter addresses the neurophysiological underpinnings of pain modulation induced by the placebo effect, emphasizing the ...
Carmen-Édith Belleï-Rodriguez   +1 more
semanticscholar   +1 more source

The Nocebo Effect: A Bias in Clinical Practice—An Ethical Approach

American Journal of Therapeutics
Background: The nocebo effect is often disregarded in medical practice and is certainly much less known than the placebo effect, although, in reality, both can influence therapeutic decision making and the quality of life of patients. However, the nocebo
Iulia-Virginia Răducan-Florea   +3 more
semanticscholar   +1 more source

The downside to choice: instrumental control increases conditioned nocebo hyperalgesia.

Pain
Nocebo hyperalgesia is a pervasive problem in which the treatment context triggers negative expectations that exacerbate pain. Thus, developing ethical strategies to mitigate nocebo hyperalgesia is crucial.
Biya Tang, E. Livesey, Ben Colagiuri
semanticscholar   +1 more source

“Powerful placebo”: A teaching and learning concept addressing placebo and nocebo effects in competency-based communication training

GMS Journal for Medical Education
Aim: Placebo and nocebo effects are based on expectations that are formed by how doctors communicate and can influence the efficacy of medical treatment. Given the implications for doctor-patient communication and the learning objectives listed in NKLM 2.
Hanna Öhlmann   +3 more
semanticscholar   +1 more source

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