Unethical informed consent caused by overlooking poorly measured nocebo effects [PDF]
, 2020 Unlike its friendly cousin the placebo effect, the nocebo effect (the effect of expecting a negative outcome) has been almost ignored. Epistemic and ethical confusions related to its existence have gone all but unnoticed.
Howick, Jeremy
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Adverse drug reactions associated with amitriptyline - protocol for a systematic multiple-indication review and meta-analysis [PDF]
, 2020 Background: Unwanted anticholinergic effects are both underestimated and frequently overlooked. Failure to identify adverse drug reactions (ADRs) can lead to prescribing cascades and the unnecessary use of over-thecounter products.
Brueckle, Maria-Sophie +9 more
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Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine [PDF]
Hospital Pharmacology, 2017 Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways.
Jakovljević Miro I.
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Frontiers in Behavioral Neuroscience, 2021 Background and Objective: Placebo and nocebo responses are widely observed. Herein, we investigated the nocebo hyperalgesia and placebo analgesia responses in brain network in acute lower back pain (ALBP) model using multivariate Granger causality ...
Yu Shi +6 more
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Information About the Optimism of a Placebo/Nocebo Provider and Placebo/Nocebo Side Effects [PDF]
Frontiers in Psychology, 2021 BackgroundResearch has demonstrated that personality characteristics, such as optimism are associated with placebo/nocebo responding. The present study investigated whether written information about the optimism of a placebo/nocebo provider can influence the occurrence of reported placebo/nocebo side effects.MethodWe analyzed data from 201 females ...
Anne Schienle, Carina Schlintl
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How does observational learning produce placebo effects? : a model integrating research findings [PDF]
, 2018 There is a growing body of evidence proving that observational learning, in addition to classical conditioning and verbal suggestions, may induce both placebo analgesia and nocebo hyperalgesia.
Bajcar, Elżbieta, Bąbel, Przemysław
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Placebo, nocebo, and neuropathic pain [PDF]
Pain, 2016 Over the last decade, the apparent increase in placebo responses in randomized controlled trials (RCTs) of neuropathic pain have complicated and potentially limited development and availability of new effective pain medication. Placebo analgesia and nocebo hyperalgesia effects are well described in nociceptive and idiopathic pain conditions, but less ...
Vase, Lene; Skyt, Ina; Hall, Kathryn T.
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Minimizing Drug Adverse Events by Informing About the Nocebo Effect—An Experimental Study
Frontiers in Psychiatry, 2019 Relevance: Informing patients about potential adverse events as part of the informed consent may facilitate the development of nocebo-driven drug adverse events (nocebo side effects).Objective: To investigate whether informing about the nocebo effect ...
Yiqi Pan +4 more
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Classical conditioning without verbal suggestions elicits placebo analgesia and nocebo hyperalgesia. [PDF]
PLoS ONE, 2017 The aim of this study was to examine the relationships among classical conditioning, expectancy, and fear in placebo analgesia and nocebo hyperalgesia. A total of 42 healthy volunteers were randomly assigned to three groups: placebo, nocebo, and control.
Przemysław Bąbel +6 more
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Nocebo and Psychological Factors in Irritable Bowel Syndrome (IBS): A Scoping Review
International Journal of Body, Mind and Culture, 2022 Background: There is considerable information about the interrelation of functional gastrointestinal disorders (FGIDs) and psychological disorders, called gut-brain interaction. Physiological and psychological variables have been linked with the etiology
Hamid Nasiri-Dehsorkhi +3 more
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