Results 51 to 60 of about 5,507 (179)

No Reason to Feel Sick? Nocebo Responses in the Placebo Arms of Experimental Endotoxemia Studies

Frontiers in Psychiatry, 2019
Adverse side effects are reported by a large proportion of patients undergoing medical treatment in clinical practice or clinical trials. Nocebo effects, induced by negative treatment expectancies, can contribute to negative patient-reported outcomes but
Sven Benson, Sigrid Elsenbruch
doaj   +1 more source

European Headache Federation recommendations for placebo and nocebo terminology

The Journal of Headache and Pain, 2020
Background and aim Despite recent publications, practitioners remain unfamiliar with the current terminology related to the placebo and nocebo phenomena observed in clinical trials and practice, nor with the factors that modulate them.
Dimos D. Mitsikostas, Charlotte Blease, Elisa Carlino, Luana Colloca, Andrew L. Geers, Jeremy Howick, Andrea W. M. Evers, Magne A. Flaten, John M. Kelley, Irving Kirsch, Regine Klinger, Antoinette MaassenVanDenBrink, Daniel E. Moerman, Petros P. Sfikakis, Lene Vase, Tor D. Wager, Fabrizio Benedetti, on behalf of the European Headache Federation   +17 more
doaj   +1 more source

Role of conditioning and verbal suggestion in placebo and nocebo effects on itch. [PDF]

PLoS ONE, 2014
Placebo and nocebo effects are known to play a key role in treatment effects in a wide variety of conditions. These effects have frequently been investigated with regard to pain and also in other physical sensations, but have hardly been investigated ...
Danielle J P Bartels, Antoinette I M van Laarhoven, Elise A Haverkamp, Oliver H Wilder-Smith, A Rogier T Donders, Henriët van Middendorp, Peter C M van de Kerkhof, Andrea W M Evers   +7 more
doaj   +1 more source

Placebo, Nocebo, and Machine Learning: How Generative AI Could Shape Patient Perception in Mental Health Care

JMIR Mental Health
The emergence of generative artificial intelligence (GenAI) in clinical settings—particularly in health documentation and communication—presents a largely unexplored but potentially transformative force in shaping placebo and nocebo effects.
C. Blease
semanticscholar   +1 more source

How does Nocebo Education lead to a Reduction in Nocebo Side Effects?: Study 2

, 2023
This study aims to investigate the underlying mechanisms through which nocebo education leads to a reduction in nocebo side ...
Michael Vang, Kim J. Görner, Ananya Chatterjee, Andrew Geers, Emily K. Spotts   +4 more
core   +1 more source

Outcomes of adalimumab biosimilar nonmedical switches in children and young adults with inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Objectives Adalimumab biosimilars are as safe and effective compared to the originator. Adult patients with inflammatory bowel disease (IBD) who switched to a biosimilar have comparable outcomes, but pediatric data are limited. This study evaluates clinical outcomes of children and young adults with IBD following a nonmedical, insurance‐driven
Daniel Himelstein, Megan McNicol, Mahmoud Abdel‐Rasoul, Brendan M. Boyle, Hilary K. Michel, Ross Maltz   +5 more
wiley   +1 more source

What Physiotherapists Specialized in Orthopedic Manual Therapy Know About Nocebo-Related Effects and Contextual Factors: Findings From a National Survey

Frontiers in Psychology, 2020
ObjectiveThe aim of this study was to investigate the knowledge of orthopedic manual therapists (OMTs) regarding context factors (CFs) capable of triggering nocebo effects during the treatment and how this knowledge is related to their socio-demographic ...
Giacomo Rossettini, Giacomo Rossettini, Tommaso Geri, Alvisa Palese, Chiara Marzaro, Mattia Mirandola, Luana Colloca, Luana Colloca, Mirta Fiorio, Andrea Turolla, Mattia Manoni, Marco Testa   +11 more
doaj   +1 more source

Informing About the Nocebo Effect Affects Patients’ Need for Information About Antidepressants—An Experimental Online Study

Frontiers in Psychiatry, 2021
Relevance: Understanding patients’ informational needs and adapting drug-related information are the prerequisites for a contextualized informed consent. Current information practices might rather harm by inducing nocebo effects.Objective: To investigate
Yvonne Nestoriuc, Yvonne Nestoriuc, Yiqi Pan, Timm Kinitz, Ella Weik, Meike C. Shedden-Mora, Meike C. Shedden-Mora   +6 more
doaj   +1 more source

Translating knowledge on placebo and nocebo effects into clinical practice

PAIN Reports
Treatment outcome is strongly influenced by treatment expectations. Modifying expectations by targeting contextual factors can substantially improve therapy success, making them a valuable focus for therapeutic interventions.
E. Caliskan, Ulrike Bingel, Angelika Kunkel   +2 more
semanticscholar   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source