Results 71 to 80 of about 4,447 (179)

Unraveling Inflammatory Pain: A Narrative Review of Molecular Pathways and Multidisciplinary Treatments

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy, Mohamed Goda Elbqry, Saddam Ahmed Al‐Ahdal, Fatima S. O. Ashmieg, Patience Osose Nasir, Nasiru Mohammed Abdullahi, Mohammed Nader Shalaby   +6 more
wiley   +1 more source

Placebo–Placebo, Nocebo–Nocebo, Placebo–Nocebo, and Nocebo–Placebo Effects: A Review of Eastern and Western Perspectives

This study examined placebo and nocebo effects, characterized by classical conditioning, operant conditioning, and expectancy effects. The placebo–placebo and nocebo–nocebo effects can be categorized to function independently, including the influence of various factors such as pill color, size, genetics (including other biological factors), branding ...
openaire   +2 more sources

The Nocebo Effect

Annual Review of Pharmacology and Toxicology
Adverse nocebo responses can cause harm to patients and interfere with treatment adherence and effects in both clinic practice and clinical trials. Nocebo responses refer to negative outcomes to active medical treatments in clinical trials or practice that cannot be explained by the treatment's pharmacologic effects.
openaire   +2 more sources

Beyond concealment: Translating placebo research into migraine care

Headache: The Journal of Head and Face Pain, EarlyView.
Julian Kleine‐Borgmann, Katharina Schmidt, Ulrike Bingel   +2 more
wiley   +1 more source

Diagnostic Features of Discogenic Low Back Pain: A Narrative Review and Suggested Areas for Future Research and Clinical Practice

JOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Chronic low back pain is a leading cause of global disability, with discogenic low back pain (DLBP), mechanically stimulated pain arising from the intervertebral disc, representing an important but often under‐recognized subtype. DLBP arises from chronic structural and metabolic changes within the intervertebral disc, leading to ...
William Roger Peters, Ashish D. Diwan, Mario Giuseppe Zotti   +2 more
wiley   +1 more source

Investigating visual effects of a disgust nocebo with fMRI [PDF]

Journal of Integrative Neuroscience, 2018
There is growing evidence that placebos are able to influence visual perception. A previous functional magnetic resonance imaging study on the processing of disgust images demonstrated that a “disgust placebo” (inert pill administered with the verbal ...
Carina Höfler, Albert Wabnegger, Anne Schienle
doaj   +1 more source

Attitudes, Beliefs, and Clinical Decision‐Making Regarding Low Back Pain: A Cross‐Sectional Study of Pakistani Medical Practitioners, Physiotherapists, and Exercise Professionals

Musculoskeletal Care, Volume 24, Issue 2, June 2026.
ABSTRACT Background Low back pain (LBP) is a leading global cause of disability, particularly burdensome in LMICs like Pakistan, where biomedical approaches remain dominant in clinical care. This study examined how healthcare professionals' (HCPs) beliefs, attitudes, and confidence influence clinical decision‐making for LBP.
Muhammad Naseeb Ullah Khan, Aastha Malhotra, Melainie Cameron   +2 more
wiley   +1 more source

‘I Want Everyone to Have It, and Everyone to Be on It’: A Feasibility Study of the Transforming Long Covid Intervention

Health Expectations, Volume 29, Issue 3, June 2026.
ABSTRACT Background An understanding of the nature of long Covid (LC) is evolving, with recent evidence highlighting the role of increased sympathetic activation and decreased parasympathetic response. Building upon this emerging science, the ‘Transforming Long COVID’ (TLC) programme was developed to support participants in their recovery by (i ...
Sarahjane Belton, Hannah Goss, Enda Whyte, Noel McCaffrey, Sophie Gibney, Kate Sheridan   +5 more
wiley   +1 more source

Beyond Malabsorption: The Need for Symptom‐Based Assessment in Suspected Lactose Intolerance. Lessons From a Test‐Specific Symptom Assessment

Neurogastroenterology &Motility, Volume 38, Issue 6, June 2026.
Breath test–proven malabsorption does not reliably predict symptoms. Many patients without malabsorption still develop significant symptoms. Symptoms after lactose ingestion are linked to fructose sensitivity and functional GI disorders. Validated, test‐specific symptom assessment is required to identify patients who may benefit from treatment ...
Johann Hammer, Heinz F. Hammer
wiley   +1 more source

Systemic Nickel Allergy Syndrome: A Critical Appraisal of an Unvalidated Diagnostic Entity

Clinical and Translational Allergy, Volume 16, Issue 5, May 2026.
ABSTRACT Systemic Nickel Allergy Syndrome (SNAS) remains a controversial clinical construct, characterized by persistent diagnostic uncertainty and the absence of reproducible biomarkers. Available studies are predominantly limited to small case series and uncontrolled observational reports, yielding partial and inconclusive findings.
Antonello Giovannetti
wiley   +1 more source