Results 71 to 80 of about 7,248 (168)

Dispositional optimism and open‐label placebo responses in hair cortisol concentrations and psychological distress—A randomized controlled trial

Applied Psychology: Health and Well-Being, Volume 18, Issue 5, October 2026.
Abstract Open‐label placebo (OLP) treatments show beneficial effects on various health‐related outcomes, but studies investigating OLP effects on physiological measures remain scarce. This randomized controlled trial examined the effect of a 4‐week OLP intervention on psychological distress and hair cortisol concentrations (HCC) in 202 healthy ...
Carolin Liedtke, Michael Schaefer, Sören Enge   +2 more
wiley   +1 more source

Placebo–Placebo, Nocebo–Nocebo, Placebo–Nocebo, and Nocebo–Placebo Effects: A Review of Eastern and Western Perspectives

This study examined placebo and nocebo effects, characterized by classical conditioning, operant conditioning, and expectancy effects. The placebo–placebo and nocebo–nocebo effects can be categorized to function independently, including the influence of ...
SHRUTHI SUKHADEV JARALI
core   +1 more source

Placebo, nocebo y Parkinson

, 2020
La información que una persona interioriza, osus propios deseos, creencias o esperanzas, puedenoriginar expectativas que, como fenómenos mentalesque son, se deben a la activación de ciertas áreascerebrales.
Vanegas F., Dr. Horacio, Vanegas, Dr. Horacio   +1 more
core   +1 more source

Peripheral Inflammation and Sleep Loss Induce Coordinated Motivational Changes: An Experimental Two‐Hit Stress Model

Journal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Sleep loss and low‐grade inflammation are common stressors that affect behaviour and recovery needs. To examine their separate and combined effects on motivation for everyday behaviours, we developed a two‐hit experimental model. Participants (N = 56, 31 women) completed three experimental visits: sleep saturation (two nights, 9 h in bed/night)
John Axelsson, Mats Lekander, Camilla I. Svensson, Nils Simon, Alexandra Kuliszkiewicz, Julie Lasselin, Leonie J. T. Balter   +6 more
wiley   +1 more source

Is there a role for implicit and explicit information about placebo and nocebo effects in reducing the use of drugs in sport? [PDF]

, 2017
Background: The gateway hypothesis posits that the use of sport supplements by athletes can lead to the use of banned and possibly harmful performance-enhancing drugs.
Beedie, C., Hurst, P., Coleman, D., Foad, A.   +3 more
core  

Short‐Term Effect of Negative Verbal Language Versus Positive Verbal Language on Physical and Functional Capacity and Pain in People With Chronic Primary Low Back Pain

European Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background Low back pain (LBP) is the leading cause of years lived with disability. While education is recommended by most guidelines, the type of language used can lead to a placebo or nocebo effect. This study aims to compare the short‐term effect of negative language versus positive language on physical and functional capacity in ...
Yves Schwendenmann, Pierre‐Antoine Palacios, Martin Descarreaux, Andrée‐Anne Marchand   +3 more
wiley   +1 more source

Mapping Pain Memory Across Modalities: Distinct Spatial Representations of Recalled Visceral and Somatic Pain

European Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background Representation of pain areas offers a spatial dimension of pain perception, yet it has rarely been used in the context of visceral pain. This experimental study examined spatial patterns of acute visceral and somatic pain and their recall.
Catrin Guddat, Genisius Hartanto, Robert J. Pawlik, Thomas Graven‐Nielsen, Sigrid Elsenbruch, Jana L. Aulenkamp   +5 more
wiley   +1 more source

The influence of the nocebo effect in clinical trials

, 2012
Luana Colloca1,2,31National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD, USA; 2National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA; 3Department of Bioethics, The ...
Colloca L
core  

Information About the Optimism of a Placebo/Nocebo Provider and Placebo/Nocebo Side Effects

, 2021
Background: Research has demonstrated that personality characteristics, such as optimism are associated with placebo/nocebo responding. The present study investigated whether written information about the optimism of a placebo/nocebo provider can ...
Schienle, Anne, Schlintl, Carina, Anne Schienle, Carina Schlintl   +3 more
core   +1 more source

Comparative Effectiveness Analysis of Phase 3 Clinical Trials in Moderately to Severely Active Inflammatory Bowel Disease Reveals Increased Harm From Placebo and Challenges Equipoise

JCC Plus, Volume 1, Issue 5, September 2026.
Across 47 Phase 3 trials in Crohn's disease and ulcerative colitis, placebo exposure was associated with measurable harm. Disease exacerbation events showed the greatest excess risk, with one additional exacerbation occurring for every 8–13 patients assigned to placebo rather than active therapy.
Joëlle St‐Pierre, Zachary D. Fine, Evan N. Fear, Jeremy A. Klein, Natalie K. Choi, David T. Rubin   +5 more
wiley   +1 more source