Results 71 to 80 of about 12,624 (267)

Placebo, nocebo, and neuropathic pain [PDF]

open access: yesPain, 2016
Over the last decade, the apparent increase in placebo responses in randomized controlled trials (RCTs) of neuropathic pain have complicated and potentially limited development and availability of new effective pain medication. Placebo analgesia and nocebo hyperalgesia effects are well described in nociceptive and idiopathic pain conditions, but less ...
Vase, Lene; Skyt, Ina; Hall, Kathryn T.
openaire   +3 more sources

Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC)

open access: yesEuropean Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Wolnei Caumo   +8 more
wiley   +1 more source

Psychological distress, perceived stress and nocebo effect (multifood adverse reaction) in irritable bowel syndrome patients

open access: yesJournal of Education and Health Promotion, 2023
BACKGROUND: Psychological distress and perceived stress may complicate the clinical presentation, course, and treatment of patients with functional gastrointestinal disorders.
Hamid Nasiri-Dehsorkhi   +3 more
doaj   +1 more source

The placebo and nocebo effects on peak minute power during incremental arm crank ergometry [PDF]

open access: yes, 2013
This is an Accepted Manuscript of an article published by Taylor & Francis Group in European Journal of Sport Science on 19 May 2014, available online: http://www.tandfonline.com/doi/abs/10.1080/17461391.2013.822564.This investigation aimed to explore ...
Andrew Nicholettos   +6 more
core   +2 more sources

Considerations for Issues of Regression to the Mean and Contextual Effects in Clinical Trials for Pain in Rheumatic Diseases

open access: yesArthritis Care &Research, Volume 78, Issue 1, Page 31-37, January 2026.
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen   +4 more
wiley   +1 more source

Exploring the Overlooked: Dutch Clinicians' Perspectives on Side Effects of Psychological Interventions

open access: yesClinical Psychology &Psychotherapy, Volume 33, Issue 1, January/February 2026.
ABSTRACT Steven J. Lynn (1946–2024) was a prolific researcher who explored a wide array of topics in clinical psychology. He and his co‐authors emphasized the importance of researching the side effects of psychological interventions. In the current studies (Study 1, N = 58; Study 2, N = 64), we examined clinicians' perspectives on side effects.
Sanne T. L. Houben   +3 more
wiley   +1 more source

Catechol-O-methyltransferase Val158Met polymorphism is associated with somatosensory amplification and nocebo responses. [PDF]

open access: yesPLoS ONE, 2014
A large number of unwanted adverse events and symptoms reported by patients in clinical trials are not caused by the drug provided, since most of adverse events also occur in corresponding placebo groups.
Laura Wendt   +8 more
doaj   +1 more source

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