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The cost of treating the major inflammatory rheumatic diseases (rheumatoid arthritis and spondyloarthritis) has increased dramatically since the advent of biotherapies (bDMARD).
O. Hagege+8 more
semanticscholar +1 more source
The Nocebo Effect: The Placebo’s “Evil Twin”
Treatments are designed to help people fight diseases or their symptoms, and they are supposed to make us feel better. However, some treatments can have unpleasant side effects.
Helena Hartmann+3 more
semanticscholar +1 more source
Nocebo effects, i.e., adverse treatment effects which are induced by patients' expectations, are known to contribute to the experience of physical symptoms such as pain and itch. A better understanding of how to minimize nocebo responses might eventually
Danielle J P Bartels+7 more
doaj +1 more source
Nocebo Effects and Scratching Behaviour on Itch [PDF]
Nocebo effects, i.e. reduced treatment effects due to patients' negative expectations, play a role in itch. Recent studies have shown that nocebo effects can be induced experimentally on itch and also be minimized and even turned into the opposite direction, i.e. placebo effects.
Bartels, D.J.P.+3 more
openaire +8 more sources
Induction and generalization of nocebo effects on itch [PDF]
AbstractNocebo effects, that is, negative treatment outcomes due to negative expectancies, can increase itch. Moreover, indirect evidence has shown that nocebo hyperknesis can generalize to another itch modality. Knowledge on response generalization can help to prevent and decrease negative effects.
Lingling Weng+3 more
openaire +6 more sources
Background: Placebo and nocebo effects on visual attention are still poorly understood. This eye-tracking study directly compared effects of sham transcranial magnetic stimulation (sTMS) that was administered along with the verbal suggestion that the ...
Carina Höfler+2 more
doaj +1 more source
Classical conditioning without verbal suggestions elicits placebo analgesia and nocebo hyperalgesia. [PDF]
The aim of this study was to examine the relationships among classical conditioning, expectancy, and fear in placebo analgesia and nocebo hyperalgesia. A total of 42 healthy volunteers were randomly assigned to three groups: placebo, nocebo, and control.
Przemysław Bąbel+6 more
doaj +1 more source
OBJECTIVES To assess the usefulness and onset of nocebo effects after switching from original etanercept (ETN) to a biosimilar (BS) in routine clinical practice at rheumatology clinics in Japan (13 sites). METHODS A total of 165 patients (87.0% female,
T. Matsubara+13 more
semanticscholar +1 more source
It is generally believed that the placebo response can elicit an analgesic effect, whilst the nocebo response can elicit a hyperalgesia effect in pain. Placebo analgesia and nocebo hyperalgesia effects are increasing concerns for researchers.
Yu Shi+7 more
doaj +1 more source
. Introduction:. Placebo and nocebo effects in pain are well documented. One leading explanation is that instructions indicating that pain will either increase or decrease after receipt of a treatment give rise to expectations for increased or decreased ...
Matthew James Coleshill+2 more
doaj +1 more source