Results 31 to 40 of about 4,230 (126)

Expectation modulates the effect of deep brain stimulation on motor and cognitive function in tremor-dominant Parkinson's disease. [PDF]

PLoS ONE, 2013
Expectation contributes to placebo and nocebo responses in Parkinson's disease (PD). While there is evidence for expectation-induced modulations of bradykinesia, little is known about the impact of expectation on resting tremor. Subthalamic nucleus (STN)
Ariane Keitel, Stefano Ferrea, Martin Südmeyer, Alfons Schnitzler, Lars Wojtecki   +4 more
doaj   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Underappreciated power. Placebo and nocebo in medicine

Медицинский совет, 2020
The term placebo is defined as a substance with no therapeutic effect that improves health by convincing the patient that the substance is effective. The term comes from the Latin “placere”, meaning “I will delight” or “do good”.
A. O. Bueverov
doaj   +1 more source

Nocebo response intensity and influencing factors in the randomized clinical trials of irritable bowel syndrome: A systematic review and meta-analysis

Frontiers in Medicine, 2022
ObjectiveTo estimate the magnitude of the nocebo response and explore its influencing factors in irritable bowel syndrome (IBS).MethodsThe PubMed, Embase, and Cochrane Library databases were searched up to March 2021.
Ruijie Li, Fuping Chen, Xuanxuan He, Yuqing Feng, Qiaoqiao Pei, Dongke Wang, Xinghuang Liu, Jinsong Liu, Xiaohua Hou, Tao Bai   +9 more
doaj   +1 more source

Time‐Resolved Multi‐Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination

Allergy, EarlyView.
We compared early vaccine‐induced immune and metabolic signatures and downstream immunity after second and booster BNT162b2 doses in participants with sARs, ISSRs, or no reactions. Neutrophil mobilization, antiviral programs, and robust anti‐S‐antibody responses occurred across reaction groups.
Ana Olivera, Benjamin Schwarz, Brittany Dulek, Ian S. LaCroix, Min Li, Lindsay Chatman, Muhammad B. Khalid, Ellen Zektser, Karen Laky, Stella Hartono, Eric Bohrnsen, Cole D. Kimzey, Eric Chu, Roa Harb, Pamela A. Frischmeyer‐Guerrerio   +14 more
wiley   +1 more source

Nocebo in Biosimilars and Generics in Neurology: A Systematic Review

Frontiers in Pharmacology, 2019
Background: Nocebo refers to adverse events related to patients’ negative expectations and previous experiences, mediated by several neurobiological pathways within the brain.
Ioanna Spanou, Theodoros Mavridis, Dimos D. Mitsikostas   +2 more
doaj   +1 more source

Do psychological interventions in childhood and adolescence prevent later mental illness? A commentary on Vassard et al. (2026)

Journal of Child Psychology and Psychiatry, EarlyView.
Early intervention in youth mental health has long been assumed to confer long‐term benefits, altering developmental trajectories and reducing risk of later mental disorders. The 3‐year follow‐up of the Mind My Mind (MMM) trial challenges these assumptions.
Ian Kelleher
wiley   +1 more source

Research Review: No robust effects of Circle of Security‐Parenting (COSP) on parenting, parents, or children – a systematic review and meta‐analysis of randomized controlled trials

Journal of Child Psychology and Psychiatry, EarlyView.
Background Circle of Security‐Parenting (COSP) is one of the most popular attachment‐based preventive support programs for parents and children. More than 50,000 participants from different (para)professional disciplines have been trained in the formal COSP™ protocol. Methods In a preregistered meta‐analysis and synthesis of all eight randomized trials
Marian J. Bakermans‐Kranenburg, Megan Galbally, Erinn Hawkins, Marinus H. van IJzendoorn   +3 more
wiley   +1 more source

Trait Neuroticism and the Nocebo Effect: The Mediating Role of Side‐Effect Expectations

Journal of Personality, EarlyView.
ABSTRACT Objective Neuroticism has not only been linked to heightened negative expectations and general somatic complaints but also to increased nocebo responses following medical treatments. Since side‐effect expectations are considered a main driver of nocebo responses, we tested whether side‐effect expectations mediate the neuroticism–nocebo ...
Anton Fischer, Li‐Ching Chuang, Nick Augustat, Pia von Blanckenburg, Erik M. Mueller   +4 more
wiley   +1 more source

Possible alleviation of symptoms and side effects through clinicians’ nocebo information and empathy in an experimental video vignette study

Scientific Reports, 2022
To alleviate anti-cancer treatment burden in advanced breast cancer, patient-clinician communication strategies based on nocebo-effect mechanisms are promising. We assessed distinct/combined effects on psychological outcomes (e.g.
M. C. Meijers, J. Stouthard, A. W. M. Evers, E. Das, H. J. Drooger, S. J. A. J. Jansen, A. L. Francke, N. Plum, E. van der Wall, Y. Nestoriuc, E. Dusseldorp, L. M. van Vliet   +11 more
doaj   +1 more source