Results 31 to 40 of about 4,003 (171)

Just Say No…to the Nocebo Effect

Inflammatory Bowel Diseases, 2020
Biosimilars are highly similar products of an innovator biologic used to decrease costs. The nocebo effect is an increase in symptoms resulting from a patient’s negative perceptions about a biosimilar. Multistep notification, organized transition, and opt-out ability constitute a framework for switching patients from a reference product to a biosimilar.
Leah, Rossmann, Raymond K, Cross
openaire   +2 more sources

Pain Anticipation and Nocebo-Related Responses: A Descriptive Mini-Review of Functional Neuroimaging Studies in Normal Subjects and Precious Hints on Pain Processing in the Context of Neurodegenerative Disorders

Frontiers in Pharmacology, 2019
The exacerbation of a clinical condition or the occurrence of negative symptoms after an inert substance dispensation or a sham treatment is known as “nocebo effect.” Nocebo is the psychobiological effect due to the negative psychosocial context that ...
Martina Amanzio, Martina Amanzio, Sara Palermo, Sara Palermo   +3 more
doaj   +1 more source

Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function

Frontiers in Psychiatry, 2020
Background: Conditioning is a key mechanism of placebo and nocebo effects in adults. Little is known about the underlying mechanisms of placebo and nocebo effects in youth and how they might be influenced by conscious awareness and cognitive abilities ...
Regula Neuenschwander, Regula Neuenschwander, Ella Weik, Christine M. Tipper, Karin Jensen, Tim F. Oberlander   +5 more
doaj   +1 more source

Expectation modulates the effect of deep brain stimulation on motor and cognitive function in tremor-dominant Parkinson's disease. [PDF]

PLoS ONE, 2013
Expectation contributes to placebo and nocebo responses in Parkinson's disease (PD). While there is evidence for expectation-induced modulations of bradykinesia, little is known about the impact of expectation on resting tremor. Subthalamic nucleus (STN)
Ariane Keitel, Stefano Ferrea, Martin Südmeyer, Alfons Schnitzler, Lars Wojtecki   +4 more
doaj   +1 more source

Placebo and the law of identification

Frontiers in Psychiatry
Thousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman, Andrew Weil, Stephen Dahmer   +2 more
doaj   +1 more source

Underappreciated power. Placebo and nocebo in medicine

Медицинский совет, 2020
The term placebo is defined as a substance with no therapeutic effect that improves health by convincing the patient that the substance is effective. The term comes from the Latin “placere”, meaning “I will delight” or “do good”.
A. O. Bueverov
doaj   +1 more source

Nocebo response intensity and influencing factors in the randomized clinical trials of irritable bowel syndrome: A systematic review and meta-analysis

Frontiers in Medicine, 2022
ObjectiveTo estimate the magnitude of the nocebo response and explore its influencing factors in irritable bowel syndrome (IBS).MethodsThe PubMed, Embase, and Cochrane Library databases were searched up to March 2021.
Ruijie Li, Fuping Chen, Xuanxuan He, Yuqing Feng, Qiaoqiao Pei, Dongke Wang, Xinghuang Liu, Jinsong Liu, Xiaohua Hou, Tao Bai   +9 more
doaj   +1 more source

The Nocebo Effect in Childbirth Classes [PDF]

The Journal of Perinatal Education, 2013
Patients are well-known to experience a placebo response to medications or treatments. It is less well-known that they can also experience a nocebo response where they have negative effects from something that should be ineffective. In recent literature, the words of medical providers have been demonstrated to create illness responses without physical ...
openaire   +2 more sources

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Nocebo in Biosimilars and Generics in Neurology: A Systematic Review

Frontiers in Pharmacology, 2019
Background: Nocebo refers to adverse events related to patients’ negative expectations and previous experiences, mediated by several neurobiological pathways within the brain.
Ioanna Spanou, Theodoros Mavridis, Dimos D. Mitsikostas   +2 more
doaj   +1 more source