Results 41 to 50 of about 3,902 (167)

Trait Neuroticism and the Nocebo Effect: The Mediating Role of Side‐Effect Expectations

Journal of Personality, EarlyView.
ABSTRACT Objective Neuroticism has not only been linked to heightened negative expectations and general somatic complaints but also to increased nocebo responses following medical treatments. Since side‐effect expectations are considered a main driver of nocebo responses, we tested whether side‐effect expectations mediate the neuroticism–nocebo ...
Anton Fischer, Li‐Ching Chuang, Nick Augustat, Pia von Blanckenburg, Erik M. Mueller   +4 more
wiley   +1 more source

Possible alleviation of symptoms and side effects through clinicians’ nocebo information and empathy in an experimental video vignette study

Scientific Reports, 2022
To alleviate anti-cancer treatment burden in advanced breast cancer, patient-clinician communication strategies based on nocebo-effect mechanisms are promising. We assessed distinct/combined effects on psychological outcomes (e.g.
M. C. Meijers, J. Stouthard, A. W. M. Evers, E. Das, H. J. Drooger, S. J. A. J. Jansen, A. L. Francke, N. Plum, E. van der Wall, Y. Nestoriuc, E. Dusseldorp, L. M. van Vliet   +11 more
doaj   +1 more source

Nocebo effects: more investigation is needed [PDF]

Expert Opinion on Drug Safety, 2018
Placebo and nocebo effects may represent a problem in drug development [1]. If, on the one hand, large and substantial placebo effects often confound the interpretation of positive outcomes in clin...
Benedetti F, Shaibani A
openaire   +3 more sources

No Evidence for Seasonal Variations in Fatigue, Sleepiness and Insomnia Symptoms: Spring Fatigue Is a Cultural Phenomenon Rather Than a Seasonal Syndrome

Journal of Sleep Research, EarlyView.
ABSTRACT Although not as prominent as in other animals, humans also experience seasonal variations in sleep duration and circadian processes. These variations are likely primarily driven by changes in photoperiod length. Anecdotally, many people report experiencing fatigue and low energy levels, particularly during spring in Germany, Switzerland and ...
Christine Blume, Albrecht Vorster
wiley   +1 more source

Negative expectations (nocebo phenomenon) in clinical interventions: A scoping review

Journal of Education and Health Promotion
Unpredictable, undesirable, and confusing reactions in the face of psychological or medical interventions make the clinical presentation more complicated and may represent clinically unexplained symptoms and also disturbed the doctor–patients ...
Hamid Nasiri-Dehsorkhi, Shahram Vaziri, Ahmad Esmaillzadeh, Peyman Adibi   +3 more
doaj   +1 more source

Placebo Analgesia, Nocebo Hyperalgesia, and the Cardiovascular System: A Qualitative Systematic Review

Frontiers in Physiology, 2020
Background: Placebo/nocebo effects involve the autonomic nervous system, including cardiac activity, but studies have reported inconsistent findings on how cardiac activity is modulated following a placebo/nocebo effect. However, no systematic review has
Hojjat Daniali, Magne Arve Flaten
doaj   +1 more source

Peripheral Inflammation and Sleep Loss Induce Coordinated Motivational Changes: An Experimental Two‐Hit Stress Model

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep loss and low‐grade inflammation are common stressors that affect behaviour and recovery needs. To examine their separate and combined effects on motivation for everyday behaviours, we developed a two‐hit experimental model. Participants (N = 56, 31 women) completed three experimental visits: sleep saturation (two nights, 9 h in bed/night)
John Axelsson, Mats Lekander, Camilla I. Svensson, Nils Simon, Alexandra Kuliszkiewicz, Julie Lasselin, Leonie J. T. Balter   +6 more
wiley   +1 more source

Beyond Malabsorption: The Need for Symptom‐Based Assessment in Suspected Lactose Intolerance. Lessons From a Test‐Specific Symptom Assessment

Neurogastroenterology &Motility, EarlyView.
Breath test–proven malabsorption does not reliably predict symptoms. Many patients without malabsorption still develop significant symptoms. Symptoms after lactose ingestion are linked to fructose sensitivity and functional GI disorders. Validated, test‐specific symptom assessment is required to identify patients who may benefit from treatment ...
Johann Hammer, Heinz F. Hammer
wiley   +1 more source

Adverse Events of Saffron (Crocus sativus L.): Systematic Review of Current Evidence

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. This systematic review aims to compile human data from studies on monopreparations of C. sativus, including stigma powder and other extracts, to evaluate their safety.
Fatemeh Sadat Hasheminasab, Mahdie Hajimonfarednejad, Seyede Maryam Najibi, Mohammad Hashem Hashempur   +3 more
wiley   +1 more source

Nocebo Effects and Scratching Behaviour on Itch [PDF]

Acta Dermato Venereologica, 2018
Nocebo effects, i.e. reduced treatment effects due to patients' negative expectations, play a role in itch. Recent studies have shown that nocebo effects can be induced experimentally on itch and also be minimized and even turned into the opposite direction, i.e. placebo effects.
Bartels, D.J.P., Laarhoven, A.I.M. van, Kerkhof, P.C.M. van de, Evers, A.W.M.   +3 more
openaire   +7 more sources