Results 21 to 30 of about 4,230 (126)

Classical conditioning without verbal suggestions elicits placebo analgesia and nocebo hyperalgesia. [PDF]

PLoS ONE, 2017
The aim of this study was to examine the relationships among classical conditioning, expectancy, and fear in placebo analgesia and nocebo hyperalgesia. A total of 42 healthy volunteers were randomly assigned to three groups: placebo, nocebo, and control.
Przemysław Bąbel, Elżbieta A Bajcar, Wacław Adamczyk, Paweł Kicman, Natalia Lisińska, Karolina Świder, Luana Colloca   +6 more
doaj   +1 more source

Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications. [PDF]

Exp Physiol
Abstract Placebo and nocebo effects on pain provide a model for investigating how cognitive and contextual factors modulate the physiological processes underlying nociception and its regulation. However, existing accounts remain fragmented and lack a unifying mechanistic framework linking brain, behaviour and autonomic responses.
Zamfira DA, Fassina T, Zaworski K, Carlino E, Rossettini G.   +4 more
europepmc   +2 more sources

No evidence that attentional bias towards pain-related words is associated with verbally induced nocebo hyperalgesia: a dot-probe study

PAIN Reports, 2021
. Introduction:. Placebo and nocebo effects in pain are well documented. One leading explanation is that instructions indicating that pain will either increase or decrease after receipt of a treatment give rise to expectations for increased or decreased ...
Matthew James Coleshill, Louise Sharpe, Ben Colagiuri   +2 more
doaj   +1 more source

Information About the Optimism of a Placebo/Nocebo Provider and Placebo/Nocebo Side Effects

Frontiers in Psychology, 2021
BackgroundResearch has demonstrated that personality characteristics, such as optimism are associated with placebo/nocebo responding. The present study investigated whether written information about the optimism of a placebo/nocebo provider can influence
Carina Schlintl, Anne Schienle
doaj   +1 more source

The Influence of Expectation on Nondeceptive Placebo and Nocebo Effects

Pain Research and Management, 2018
Nondeceptive placebo has demonstrated its efficiency in clinical practice. Although the underlying mechanisms are still unclear, nondeceptive placebo effect and nondeceptive nocebo effect may be mediated by expectation.
Hua Wei, Lili Zhou, Huijuan Zhang, Jie Chen, Xuejing Lu, Li Hu   +5 more
doaj   +1 more source

Differential Classical Conditioning of the Nocebo Effect: Increasing Heat-Pain Perception without Verbal Suggestions

Frontiers in Psychology, 2017
Background: Nocebo effects, including nocebo hyperalgesia, are a common phenomenon in clinical routine with manifold negative consequences. Both explicit expectations and learning by conditioning are known to induce nocebo effects, but the specific role ...
Anne-Kathrin Bräscher, Anne-Kathrin Bräscher, Dieter Kleinböhl, Dieter Kleinböhl, Rupert Hölzl, Rupert Hölzl, Susanne Becker, Susanne Becker   +7 more
doaj   +1 more source

Pain Anticipation and Nocebo-Related Responses: A Descriptive Mini-Review of Functional Neuroimaging Studies in Normal Subjects and Precious Hints on Pain Processing in the Context of Neurodegenerative Disorders

Frontiers in Pharmacology, 2019
The exacerbation of a clinical condition or the occurrence of negative symptoms after an inert substance dispensation or a sham treatment is known as “nocebo effect.” Nocebo is the psychobiological effect due to the negative psychosocial context that ...
Martina Amanzio, Martina Amanzio, Sara Palermo, Sara Palermo   +3 more
doaj   +1 more source

Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function

Frontiers in Psychiatry, 2020
Background: Conditioning is a key mechanism of placebo and nocebo effects in adults. Little is known about the underlying mechanisms of placebo and nocebo effects in youth and how they might be influenced by conscious awareness and cognitive abilities ...
Regula Neuenschwander, Regula Neuenschwander, Ella Weik, Christine M. Tipper, Karin Jensen, Tim F. Oberlander   +5 more
doaj   +1 more source

A comparison of placebo and nocebo effects on objective and subjective postural stability: a double-edged sword?

Frontiers in Human Neuroscience, 2022
Background: Positive expectations (i.e., placebo effect) can improve postural control during quiet standing. This raises an important question: if postural control is susceptible to positive expectations, is it possible to elicit the opposite, a decline ...
Katherine Russell, Michael Duncan, Michael Price, Amber Mosewich, Toby Ellmers, Mathew Hill   +5 more
doaj   +1 more source

Placebo and the law of identification

Frontiers in Psychiatry
Thousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman, Andrew Weil, Stephen Dahmer   +2 more
doaj   +1 more source