Results 51 to 60 of about 3,902 (167)

‘Living Well With a PICC at Home’: Co‐Design and Evaluation of a Peripherally Inserted Central Catheter (PICC) Booklet

open access: yesJournal of Advanced Nursing, Volume 82, Issue 5, Page 5348-5358, May 2026.
ABSTRACT Aim To co‐design an information booklet to support adults living with a peripherally inserted central catheter (PICC) at home. Design A sequential, mixed‐method approach using Boyd's co‐design framework. Method A diverse project team led co‐design of a PICC booklet based on preferences and PICC management strategies identified through content ...
Rebecca Sharp   +10 more
wiley   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1023-1039, April 2026.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran   +2 more
wiley   +1 more source

Nocebo and pain: an overview of the psychoneurobiological mechanisms

open access: yesPAIN Reports, 2017
. Introduction:. Nocebo effects are defined as adverse events related to negative expectations and learning processes that are involved in the modulation of the descending pain pathways.
Maxie Blasini   +3 more
doaj   +1 more source

Double‐Blind Placebo Challenge Confirmation of Diphenhydramine Allergy

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Diphenhydramine, a first‐generation H1–antihistamine commonly used for allergic symptom relief and infusion premedication, rarely causes true systemic hypersensitivity. When suspected reactions are mild and subjective—particularly in anxious patients—objective confirmation is essential.
Ruchi Patel   +2 more
wiley   +1 more source

Risk factors associated with nocebo effects: A review of reviews

open access: yesBrain, Behavior, & Immunity - Health
Objective: This meta-review aims to identify and categorize the risk factors that are associated with nocebo effects. The nocebo effect can exert a negative impact on treatment outcomes and have detrimental outcomes on health.
Francesca Grosso   +4 more
doaj   +1 more source

Placebo and nocebo effects in the neurological practice

open access: yesArquivos de Neuro-Psiquiatria, 2015
Knowledge of placebo and nocebo effects is essential to identify their influence on the results in clinical practice and clinical trials, and thereby properly interpret their results.
Caroline Bittar, Osvaldo J.M. Nascimento
doaj   +1 more source

Beyond concealment: Translating placebo research into migraine care

open access: yes
Headache: The Journal of Head and Face Pain, EarlyView.
Julian Kleine‐Borgmann   +2 more
wiley   +1 more source

Sex Differences in Statin Intolerance: Insights From the CLEAR Outcomes Trial

open access: yesClinical Cardiology, Volume 49, Issue 4, April 2026.
The global CLEAR Outcomes Trial was notable for enrolling 48% females. The study data set offers a unique opportunity to identify any differences in demographics, clinical characteristics, and tolerability of treatment with bempedoic acid between females and males with statin intolerance.
Sahar Naderi   +9 more
wiley   +1 more source

Visual placebo and nocebo effects

open access: yesThe Journal of Physiology
AbstractPlacebo and nocebo effects modulate symptom perception through expectations and learning processes in various domains. Predominantly, their impact has been investigated on pain and physical performance. However, the influence of placebos and nocebos on visual system functionality has yet to be explored.
Piedimonte, Alessandro   +6 more
openaire   +2 more sources

Placebo Effect on Pain‐Related Autonomic Responses in a State of Experimentally‐Induced Sensitization

open access: yesEuropean Journal of Pain, Volume 30, Issue 4, April 2026.
ABSTRACT Background Pain‐related autonomic responses are increased after experimentally‐induced secondary mechanical hyperalgesia (SMH), as well as in a variety of chronic pain cohorts. In this state of sensitization, negative expectations further amplify these enhanced responses.
Florin Allmendinger   +5 more
wiley   +1 more source

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