Results 71 to 80 of about 9,390 (248)

Nocebo effects: more investigation is needed [PDF]

open access: yesExpert Opinion on Drug Safety, 2018
Placebo and nocebo effects may represent a problem in drug development [1]. If, on the one hand, large and substantial placebo effects often confound the interpretation of positive outcomes in clin...
Benedetti F, Shaibani A
openaire   +3 more sources

Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC)

open access: yesEuropean Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Wolnei Caumo   +8 more
wiley   +1 more source

Negative expectations (nocebo phenomenon) in clinical interventions: A scoping review

open access: yesJournal of Education and Health Promotion
Unpredictable, undesirable, and confusing reactions in the face of psychological or medical interventions make the clinical presentation more complicated and may represent clinically unexplained symptoms and also disturbed the doctor–patients ...
Hamid Nasiri-Dehsorkhi   +3 more
doaj   +1 more source

The effect of varying practitioner communication on patients' health status and treatment outcomes [PDF]

open access: yes, 2011
This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of interventions in which healthcare practitioner communication in face-to-face consultations with patients is experimentally varied in ...
Ader   +52 more
core   +1 more source

Considerations for Issues of Regression to the Mean and Contextual Effects in Clinical Trials for Pain in Rheumatic Diseases

open access: yesArthritis Care &Research, Volume 78, Issue 1, Page 31-37, January 2026.
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen   +4 more
wiley   +1 more source

Nocebo and pain: an overview of the psychoneurobiological mechanisms

open access: yesPAIN Reports, 2017
. Introduction:. Nocebo effects are defined as adverse events related to negative expectations and learning processes that are involved in the modulation of the descending pain pathways.
Maxie Blasini   +3 more
doaj   +1 more source

Types of Control in Acupuncture Clinical Trials Might Affect the Conclusion of the Trials: A Review of Acupuncture on Pain Management [PDF]

open access: yes, 2016
published_or_final_versio
Chen, H   +8 more
core   +1 more source

Exploring the Overlooked: Dutch Clinicians' Perspectives on Side Effects of Psychological Interventions

open access: yesClinical Psychology &Psychotherapy, Volume 33, Issue 1, January/February 2026.
ABSTRACT Steven J. Lynn (1946–2024) was a prolific researcher who explored a wide array of topics in clinical psychology. He and his co‐authors emphasized the importance of researching the side effects of psychological interventions. In the current studies (Study 1, N = 58; Study 2, N = 64), we examined clinicians' perspectives on side effects.
Sanne T. L. Houben   +3 more
wiley   +1 more source

Placebo Analgesia, Nocebo Hyperalgesia, and the Cardiovascular System: A Qualitative Systematic Review

open access: yesFrontiers in Physiology, 2020
Background: Placebo/nocebo effects involve the autonomic nervous system, including cardiac activity, but studies have reported inconsistent findings on how cardiac activity is modulated following a placebo/nocebo effect. However, no systematic review has
Hojjat Daniali, Magne Arve Flaten
doaj   +1 more source

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