Results 71 to 80 of about 13,698,123 (253)

Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function

Frontiers in Psychiatry, 2020
Background: Conditioning is a key mechanism of placebo and nocebo effects in adults. Little is known about the underlying mechanisms of placebo and nocebo effects in youth and how they might be influenced by conscious awareness and cognitive abilities ...
Regula Neuenschwander, Regula Neuenschwander, Ella Weik, Christine M. Tipper, Karin Jensen, Tim F. Oberlander   +5 more
doaj   +1 more source

Path-Free Decomposition for Direct, Indirect and Interaction Effects in Mediation Analysis [PDF]

arXiv, 2021
Given a binary treatment and a binary mediator, mediation analysis decomposes the total effect of the treatment on an outcome variable into direct and indirect effects. However, the existing decompositions are "path-dependent", and consequently, there appeared different versions of direct and indirect effects.
arxiv  

Considering the nocebo effect in the psychedelic discourse

Journal of Psychedelic Studies
This commentary addresses the potential for a nocebo effect arising from the public discourse on psychedelics, especially considering the increasing interest and engagement with these substances.
Maria Bălăeţ
semanticscholar   +1 more source

Pain Anticipation and Nocebo-Related Responses: A Descriptive Mini-Review of Functional Neuroimaging Studies in Normal Subjects and Precious Hints on Pain Processing in the Context of Neurodegenerative Disorders

Frontiers in Pharmacology, 2019
The exacerbation of a clinical condition or the occurrence of negative symptoms after an inert substance dispensation or a sham treatment is known as “nocebo effect.” Nocebo is the psychobiological effect due to the negative psychosocial context that ...
Martina Amanzio, Martina Amanzio, Sara Palermo, Sara Palermo   +3 more
doaj   +1 more source

A comparison of placebo and nocebo effects on objective and subjective postural stability: a double-edged sword?

Frontiers in Human Neuroscience, 2022
Background: Positive expectations (i.e., placebo effect) can improve postural control during quiet standing. This raises an important question: if postural control is susceptible to positive expectations, is it possible to elicit the opposite, a decline ...
Katherine Russell, Michael Duncan, Michael Price, Amber Mosewich, Toby Ellmers, Mathew Hill   +5 more
doaj   +1 more source

Handling Higher-Order Effects [PDF]

arXiv, 2022
Algebraic effect handlers is a programming paradigm where programmers can declare their own syntactic operations, and modularly define the semantics of these using effect handlers. However, we cannot directly define algebraic effect handlers for many higher-order operations (or higher-order effects) -- i.e., operations that have computations as ...
arxiv  

Assessing the longevity of attribute framing in attenuating the nocebo effect to brand and generic medication.

Applied Psychology: Health and Well-Being
The perception of taking a generic, relative to brand, medication has been demonstrated to exacerbate the nocebo effect. Conversely, positive attribute framing has been shown to attenuate the nocebo effect. However, little is known about the longevity of
Kirsten Barnes, Kurt Sydney, Kristina Petkovich, Yasmin Hasan, Saakshi Koul, Kiarne Humphreys, Andrew L. Geers, Kate Faasse   +7 more
semanticscholar   +1 more source

Underappreciated power. Placebo and nocebo in medicine

Медицинский совет, 2020
The term placebo is defined as a substance with no therapeutic effect that improves health by convincing the patient that the substance is effective. The term comes from the Latin “placere”, meaning “I will delight” or “do good”.
A. O. Bueverov
doaj   +1 more source

Nocebo response intensity and influencing factors in the randomized clinical trials of irritable bowel syndrome: A systematic review and meta-analysis

Frontiers in Medicine, 2022
ObjectiveTo estimate the magnitude of the nocebo response and explore its influencing factors in irritable bowel syndrome (IBS).MethodsThe PubMed, Embase, and Cochrane Library databases were searched up to March 2021.
Ruijie Li, Fuping Chen, Xuanxuan He, Yuqing Feng, Qiaoqiao Pei, Dongke Wang, Xinghuang Liu, Jinsong Liu, Xiaohua Hou, Tao Bai   +9 more
doaj   +1 more source

A single‐centre analysis of a biosimilar switching programme for adalimumab in inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Aims Amgevita is a licensed biosimilar to adalimumab, having demonstrated high pharmacokinetic and clinical similarity to Humira. Switching to a lower‐cost medicine may elicit a nocebo effect, whereby expectations of poorer efficacy impact outcomes despite pharmacological similarity. This prospective cohort study examined clinical and economic outcomes
Louise Rabbitt, Áine Keogh, Linda Duane, John Ferguson, Anna Hobbins, Brian E. McGuire, Patrick Gillespie, Laurence J. Egan   +7 more
wiley   +1 more source