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Nocebo effect, originally denoting the negative counterpart of the placebo phenomenon, is now better defined as the occurrence of adverse effects to a therapeutic intervention because the patient expects them to develop. More commonly encountered in patients with a past negative experience, this effect stems from highly active processes in the central ...
Sidharth, Sonthalia +7 more
openaire +2 more sources
Introducing the 'Drucebo' Effect in Statin Therapy: A systematic review of studies comparing reported rates of statin-associated muscle symptoms, under blinded and open-label conditions. [PDF]
Background: The ‘placebo effect’ and ‘nocebo effect’ are phenomena whereby beneficial (placebo) or adverse (nocebo) effects result from the expectation that an inert substance will relieve or cause a particular symptom.
Banach +38 more
core +2 more sources
Catechol-O-methyltransferase Val158Met polymorphism is associated with somatosensory amplification and nocebo responses. [PDF]
A large number of unwanted adverse events and symptoms reported by patients in clinical trials are not caused by the drug provided, since most of adverse events also occur in corresponding placebo groups.
Laura Wendt +8 more
doaj +1 more source
Prescribing placebos ethically: the appeal of negatively informed consent [PDF]
Kihlbom has recently argued that a system of seeking negatively informed consent might be preferable in some cases to the ubiquitous informed consent model. Although this theory is perhaps not powerful enough to supplant informed consent in most settings,
Shaw, D.M.
core +1 more source
Relieving pain using dose-extending placebos [PDF]
Placebos are often used by clinicians, usually deceptively and with little rationale or evidence of benefit, making their use ethically problematic. In contrast with their typical current use, a provocative line of research suggests that placebos can be ...
Colloca, Luana +2 more
core +1 more source
. Introduction:. Placebo and nocebo effects in pain are well documented. One leading explanation is that instructions indicating that pain will either increase or decrease after receipt of a treatment give rise to expectations for increased or decreased ...
Matthew James Coleshill +2 more
doaj +1 more source
The placebo and nocebo effects on peak minute power during incremental arm crank ergometry [PDF]
This is an Accepted Manuscript of an article published by Taylor & Francis Group in European Journal of Sport Science on 19 May 2014, available online: http://www.tandfonline.com/doi/abs/10.1080/17461391.2013.822564.This investigation aimed to explore ...
Andrew Nicholettos +6 more
core +2 more sources
This comprehensive review summarizes and interprets the neurobiological correlates of nocebo hyperalgesia in healthy humans. Nocebo hyperalgesia refers to increased pain sensitivity resulting from negative experiences and is thought to be an important ...
Mia A. Thomaidou +10 more
doaj +1 more source
The effect of placebo and neurophysiological involvements [PDF]
Placebo and placebo effect are important issues related to the drug therapy for clinical and scientific meanings. The rates of placebo may get as many as 50% for analgesic drugs in headache. The high answer to placebo brings questions on pathophysiology
Galli, Federica +2 more
core +1 more source
Nonadherence to statins:individualized intervention strategies outside the pill box [PDF]
Poor adherence to statin therapy is linked to significantly increased risk of cardiovascular events and death. Unfortunately, adherence to statins is far from optimal.
Lansberg, Peter +4 more
core +5 more sources

