Results 111 to 120 of about 97,568 (259)

Analgesic use, safety and pharmacokinetics of acetaminophen in equids: A structured scoping review

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Despite its frequent use in equine clinical practice, scientific data on the use of acetaminophen in horses remain limited. Objective To map and critically appraise the available evidence on the analgesic use, safety and pharmacokinetics of acetaminophen in horses. Study Design Structured scoping review.
Francisco Medina‐Bautista   +2 more
wiley   +1 more source

The nociceptive response during adult cardiac surgery measured by the qNOX index: A feasibility study

open access: yes
Background. Monitoring nociception during general anaesthesia remains a substantial challenge. The Conox monitor uses two EEG indices, the qCon and the qNox.
Marek Maly   +4 more
core   +1 more source

Assessment of the wind-up phenomenon in the equine nociceptive trigeminal system.

open access: yes, 2013
Repeated sub-threshold nociceptive electrical stimulation resulting in temporal summation of the limb nociceptive withdrawal reflex is a well-established non-invasive model to investigate the wind-up phenomenon in horses.
Spadavecchia, Claudia   +8 more
core   +1 more source

Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage

open access: yesExploration, EarlyView.
Osteoarthritis pain arises not only from joint damage but also from inflammation, abnormal bone changes, and excessive nerve activation inside the joint. In this study, we developed an injectable nanomedicine, LAC, that responds to the acidic environment of osteoarthritic joints to locally release two approved drugs, reducing inflammation, limiting ...
Junyan Liu   +12 more
wiley   +1 more source

Botulinum Toxin for First Bite Syndrome: A Symptom‐Guided “Follow‐The‐Pain” Injection Strategy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background To evaluate botulinum toxin type A (BoNT‐A) for First Bite Syndrome (FBS) and assess a symptom‐guided “Follow‐the‐Pain” (FTP) injection strategy in patients with incomplete response to standard treatment. Methods Consecutive patients with postoperative FBS were treated with ultrasound‐guided intraparotid BoNT‐A injection.
Rosario Marchese‐Ragona   +5 more
wiley   +1 more source

Exploration of nociceptive and non-nociceptive cortical processing with steady-state evoked potentials

open access: yes, 2011
The periodic presentation of a sensory stimulus induces, at certain frequencies of stimulation, a sustained electroencephalographic response known as steady-state evoked potentials (SS-EP). In the somatosensory, visual and auditory modalities, SS-EPs are
Colon, Elisabeth   +2 more
core  

Thermo-nociceptive interaction

open access: yes, 2019
Thermo-nociceptive interaction: inter-channel pain modulation occurs before intra-channel convergence of ...
elisa raffaella ferre   +2 more
core   +1 more source

EEG frequency-tagging to dissociate the cortical responses to nociceptive and non-nociceptive stimuli

open access: yes, 2013
Whether the cortical processing of nociceptive input relies on the activity of nociceptive-specific neurons or whether it relies on the activity of non-specific neuronal populations remains a matter of intense debate. Here, we address this question using
Colon, Elisabeth   +3 more
core  

Effects of opioid blockade on nociceptive flexion reflex thresholds and nociceptive responding in hypertensive and normotensive individuals.

open access: yes, 2008
Hypertension and risk for hypertension have been associated with reduced pain sensitivity. It has been hypothesised that endogenous opioids contribute to this hypertensive hypoalgesia.
Edwards, Louisa   +4 more
core   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

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