Results 101 to 110 of about 89,362 (300)

Poor judgment of distance between nociceptive stimuli [PDF]

, 2015
Although pain is traditionally assumed to be poorly localized, recent work indicates that spatial acuity for nociception is surprisingly high. Here we investigated whether the nervous system can also accurately estimate the distance between two ...
Mancini, Flavia, Steinitz, H, Iannetti, GD, Steinitz, Hannah, Haggard, P, Iannetti, Gian Domenico, Haggard, Patrick, ,, Mancini, F, Steckelmacher, J, Steckelmacher, James   +10 more
core   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Ion Channels of Nociception [PDF]

International Journal of Molecular Sciences, 2020
The special issue “Ion Channels of Nociception” contains 13 articles published by 73 authors from different countries united by the main focusing on the peripheral mechanisms of pain. The content covers the mechanisms of neuropathic, inflammatory, and dental pain as well as pain in migraine and diabetes, nociceptive roles of P2X3, ASIC, Piezo and TRP ...
openaire   +2 more sources

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker, Katherine D. Wysham, Mercedes Quinones, Bryant R. England, Kaitian Jin, Marianna Olave, Sarah Wetzel, Rachel L. Gillcrist, Criswell Lavery, Natalie Keller, Bridget Kramer, Bibianna Ateh, Hannah Brubeck, Daniel K. White, Alexis Ogdie, Rui Xiao, Tuhina Neogi, Carla R. Scanzello   +17 more
wiley   +1 more source

Complex Regional Pain Syndrome: Why Does Pain Spread From the Injured Limb to the Face?

, 2009
In patients with complex regional pain syndrome (CRPS), sensory disturbances commonly spread outside the affected limb, in particular hemilaterally. Hyperalgesia to pressure-pain was, for instance, documented in the forehead ipsilateral to the affected ...
Knudsen, Lone
core  

A Review of the Effects of Transcutaneous Electrical Nerve Stimulation upon the RIII Nociceptive Reflex

, 2000
© 2000 Maney Publishing. Transcutaneous electrical nerve stimulation (TENS) is a popular modality for the management of pain, despite a lack of consensus regarding the optimal analgesic stimulation parameters.
Lowe, Andrea S., Walsh, Deirdre M., Cramp, Fiona L.A., Deirdre M. Walsh, Andrea S. Lowe, Cramp, Fiona (Alice), Fiona L. A. Cramp   +6 more
core   +1 more source

Arthroscopic Radial Styloidectomy: An All‐Dorsal Two‐Portal Surgical Technique

Arthroscopy Techniques, EarlyView.
Abstract Radial‐sided wrist pain and impingement are recognized sources of persistent symptoms following 4‐corner fusion, often related to radioscaphoid contact and progressive degenerative changes. Radial styloidectomy has been described as a surgical option to address this pathology while preserving carpal stability.
Frank L. Vazquez, Anna L. Gorsky, Kier Blevins, Krishna N. Chopra, Nina Suh, Eric R. Wagner   +5 more
wiley   +1 more source

Fibromyalgia and Nociceptive Flexion Reflex (NFR) Threshold: A Systematic Review, Meta-Analysis, and Identification of a Possible Source of Heterogeneity

, 2021
Mohammadreza Amiri,1 Jamie Rhudy,2 Kei Masani,1,3 Dinesh Kumbhare1,3 1KITE Research Institute, University Health Network, Toronto, ON, M5G 2A2, Canada; 2College of Arts & Sciences Psychology, University of Tulsa, Tulsa, OK, 74104, USA; 3Department of
Amiri M, Masani K, Rhudy J, Kumbhare D
core  

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Nociceptive Local Field Potentials Recorded from the Human Insula Are Not Specific for Nociception.

PLoS Biology, 2016
The insula, particularly its posterior portion, is often regarded as a primary cortex for pain. However, this interpretation is largely based on reverse inference, and a specific involvement of the insula in pain has never been demonstrated.
Giulia Liberati, Anne Klöcker, Marta M Safronova, Susana Ferrão Santos, Jose-Geraldo Ribeiro Vaz, Christian Raftopoulos, André Mouraux   +6 more
doaj   +1 more source