Results 131 to 140 of about 27,783 (192)

Peripheral Nociceptors

, 2009
openaire   +1 more source

Neuroimmune interactions in arthritis: linking pain sensitisation and inflammation. [PDF]

J Bone Miner Metab
Sow TTM, Hasegawa T.
europepmc   +1 more source

Cellular and molecular changes in the skin driving increased nociception and pain during burn injury and repair. [PDF]

Front Pain Res (Lausanne)
Nappi C, Taberner FJ.
europepmc   +1 more source

Studying human nociceptors: from fundamentals to clinic [PDF]

Brain, 2021
Chronic pain affects one in five of the general population and is the third most important cause of disability-adjusted life-years globally. Unfortunately, treatment remains inadequate due to poor efficacy and tolerability.
Steven J Middleton, Andreas C Themistocleous, Patrick M. Dougherty   +2 more
exaly   +2 more sources

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Neurotrophins, nociceptors, and pain

Microscopy Research and Technique, 1999
It is now well established that neurotrophins play a crucial role in the development of the nervous system. However, there is increasing evidence that the function of neurotrophins persists throughout adulthood. The broad scope of neurotrophin action is well documented in the case of nerve growth factor (NGF) and its effect on nociceptors and ...
L M, Mendell, K M, Albers, B M, Davis
openaire   +2 more sources

Neurotrophins, nociceptors and pain

Current Opinion in Anaesthesiology, 2000
Nerve growth factor (NGF) is known to play a key role in the development of hyperalgesia after inflammatory injury. The increased levels of NGF that accompany injury lead to hyperalgesia via peripheral and central spinal mechanisms. New evidence reviewed here indicates that NGF can directly sensitize nociceptive neurones to noxious heat stimuli through
P A, Heppenstall, G R, Lewin
openaire   +2 more sources

Nociceptor activation and pain

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985
Abstract This paper reviews advances in our knowledge on the physiological properties of human nociceptors and their capacity to signal pain. Conventional microneurography was used in combination with intraneural microstimulation in subjects who estimated the magnitude of pain from nociceptor stimulation.
openaire   +2 more sources

Nociceptors of the Joint with Particular Reference to Silent Nociceptors

2007
This chapter summarizes recent research on mechanisms by which diseased joints become painful. Joints are supplied with sensory AΒ, Aδ and C fibers.
openaire   +1 more source