Results 131 to 140 of about 22,526 (252)

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang, Linlin Xu, Chenglong Pan, Ruonan Cao, Piao Zeng, Xinxing Lyu, Qingxia Hu, Zhenzhen Yan, Shuhong Huang, Ningning Dang   +9 more
wiley   +1 more source

Electrophysiological Properties and Mechanical Sensitivity of Trigeminal Ganglionic Neurons That Innervate the Maxillary Sinus in Mice. [PDF]

Int J Mol Sci
Gupta S, Sharma AR, Ling J, Godley F, Gu J.   +4 more
europepmc   +1 more source

Kv7 and K2P Potassium Channels in Thalamocortical Function and Their Therapeutic Potential in Childhood Absence Epilepsy

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Modulation of K2P and Kv7 channels has the potential to reduce hyperexcitability and hypersynchronicity within the thalamocortical system. This offers a new avenue to suppress spike and wave discharges, the electrophysiological hallmark of absence epilepsy.
Anushka Takhi, Guiscard Seebohm, Thomas Budde, Annika Lüttjohann   +3 more
wiley   +1 more source

Piezo2 mediates mechanical sensitivity and injury-induced hypersensitivity in MrgprD-expressing nociceptors. [PDF]

Pain
Fernández-Trillo J, Villaro-Capellán M, de la Peña E, Viana F, Gomis A.   +4 more
europepmc   +1 more source

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1339-1349, June 2026.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller, Steven E. Harte, Richard E. Harris, Andrew Schrepf, Tristin Smith, Eric Ichesco, Chelsea Kaplan, Flavia Sunzini, Deeba Minhas, Wendy Marder, Sara R. Till, David A. Williams, Chad M. Brummett, Neil Basu, Sawsan As‐Sanie, Daniel J. Clauw   +15 more
wiley   +1 more source

Neuroimmune interactions in arthritis: linking pain sensitisation and inflammation. [PDF]

J Bone Miner Metab
Sow TTM, Hasegawa T.
europepmc   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, Volume 101, Issue 3, Page 1311-1333, June 2026.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

Neuro-Immune Axis in Trauma-Induced Heterotopic Ossification: Mechanisms and Therapeutic Implications. [PDF]

Cells
Agu OJ, Pereira C, Gupta I, Moran A, Mokhtari T.   +4 more
europepmc   +1 more source

The Effect of Ozone Therapy on Psoriasis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Psoriasis is an immune‐mediated skin disease in which genetic and environmental factors have a significant role. Olive oil with antioxidant properties is an effective adjunct treatment for skin diseases. Furthermore, ozone by introducing O2 into the bloodstream controls the response of cell‐mediated immunity and leads to improve disease.
Maryam Aghaei, Shahrzad Aghaei, Zabihollah Shahmoradi, Mohammad‐Ali Nilforoushzadeh, Seyed Hossein Hejazi   +4 more
wiley   +1 more source

C-C motif chemokine ligand 12 (CCL12) is a critical chemokine driving postoperative pain. [PDF]

Pain
de Souza S, Hua H, Laumet S, Sim J, Vanacker C, Bavencoffe A, Laumet G.   +6 more
europepmc   +1 more source