Results 161 to 170 of about 49,496 (354)

Expression profiles of TRPV1, TRPV4, TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced neuropathy rat model

, 2018
Background: The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life.
Elsadek, Bakheet, Maqboul, Ahmad
core   +2 more sources

Novel classes of responsive and unresponsive C nociceptors in human skin [PDF]

, 1995
Roland Schmidt, Martin Schmelz, Clemens Forster, Matthias Ringkamp, Erik Torebjörk, H. O. Handwerker   +5 more
openalex   +1 more source

A protocol to differentiate nociceptors, mechanoreceptors, and proprioceptors from human pluripotent stem cells

, 2022
Kenyi Saito‐Diaz, Nadja Zeltner
openalex   +1 more source

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

Experimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela, Anuja R. Bony, Sonia Garcia‐Caraballo, David J. Adams, Stuart M. Brierley   +4 more
wiley   +1 more source

From pain to tumor immunity: influence of peripheral sensory neurons in cancer

Frontiers in Immunology
The nervous and immune systems are the primary sensory interfaces of the body, allowing it to recognize, process, and respond to various stimuli from both the external and internal environment.
Ugo Mardelle, Ninon Bretaud, Clara Daher, Vincent Feuillet   +3 more
doaj   +1 more source

Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice [PDF]

, 2020
Diana Tavares‐Ferreira, Pradipta Ray, Ishwarya Sankaranarayanan, Galo L. Mejia, Andi Wangzhou, Stephanie Shiers, Ruta Uttarkar, Salim Megat, Paulino Barragán‐Iglesias, Gregory Dussor, Armen N. Akopian, Theodore J. Price   +11 more
openalex   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Nociceptor Overexpression of NaV1.7 Contributes to Chronic Muscle Pain Induced by Early-Life Stress

, 2021
Pedro Álvarez, Oliver Bogen, Paul G. Green, Jon D. Levine   +3 more
openalex   +2 more sources

Exaptation and Evolutionary Adaptation in Nociceptor Mechanisms Driving Persistent Pain [PDF]

, 2023
Edgar T. Walters
openalex   +1 more source

Local Injection of a Selective Endothelin-B Receptor Agonist Inhibits Endothelin-1-Induced Pain-Like Behavior and Excitation of Nociceptors in a Naloxone-Sensitive Manner [PDF]

, 2002
Alla Khodorova, Moin U. Fareed, A. P. Gokin, Gary R. Strichartz, Gudarz Davar   +4 more
openalex   +1 more source