Results 201 to 210 of about 49,496 (354)

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li   +7 more
wiley   +1 more source

The Myofascial Continuum: Anatomical Insights Into Noncardiac Chest Pain

open access: yesClinical Anatomy, Volume 39, Issue 1, Page 2-8, January 2026.
ABSTRACT Angina, commonly known as chest pain, is the primary symptom of ischemic heart disease and can also present as pain in the neck, shoulder, jaw, arm, or back. Noncardiac chest pain (NCCP) is a common disorder with various causes, marked by recurrent chest pain that mimics ischemic heart pain.
Prabu Raja G   +3 more
wiley   +1 more source

Colon Innervating TRPA1 Positive Nociceptors Influence Mucosal Health In Mice [PDF]

open access: gold, 2021
Vibhu Kumar   +9 more
openalex   +1 more source

Effects of Aging on Pain Tolerance: A Comparative Study of Heat Pain Thresholds and Tonic Heat and Cold Stimuli

open access: yesEuropean Journal of Pain, Volume 30, Issue 1, January 2026.
ABSTRACT Introduction Aging is known to impact both pain perception and modulation. While sensory thresholds have been extensively studied, age‐related changes in pain tolerance remain less conclusive. Additionally, limited research has explored whether thermal modality differentially affects pain tolerance in older adults.
Julia Devanne, Louise Trocmet
wiley   +1 more source

A Probabilistic Model for Estimating the Depth and Threshold Temperature of C-fiber Nociceptors [PDF]

open access: gold, 2015
Tara Dezhdar   +4 more
openalex   +1 more source

Reduced Descending Itch Inhibition in Peripheral Neuropathy Patients With Chronic Pruritus

open access: yesEuropean Journal of Pain, Volume 30, Issue 1, January 2026.
ABSTRACT Background Peripheral neuropathies (PNP) cause a wide range of symptoms of which pruritus and pain are a major burden to patients. Clarifying their mechanisms will facilitate the adequate symptom management. In contrast to neuropathic pain, neuropathic pruritus has long been understudied.
Jonas Eck   +9 more
wiley   +1 more source

Response to High‐Dose Topical Capsaicin in Neuropathic Pain: Absence of Deep Pain as a Predictor of Analgesic Effect

open access: yesEuropean Journal of Pain, Volume 30, Issue 1, January 2026.
ABSTRACT Background Topical high‐dose capsaicin treatment is a recommended therapy for localised neuropathic pain with good tolerability and no identified drug interactions. However, it is not effective for every patient. So far, few parameters in patient history have been identified as predictors for response to capsaicin treatment.
Manon Sendel   +11 more
wiley   +1 more source

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