Results 81 to 90 of about 3,343 (187)

The insula represents a key neurobiological pain hub in psoriatic arthritis

Arthritis Research & Therapy
Background Pain remains a principal complaint for people with psoriatic arthritis (PsA), despite successful mitigation of inflammation. This situation alludes to the co-existence of distinct pain mechanisms.
Flavia Sunzini, Kristian Stefanov, Salim Al-Wasity, Chelsea Kaplan, Andrew Schrepf, Noah Waller, Steven Harte, Richard Harris, Daniel J. Clauw, John McLean, Stefan Siebert, Carl S. Goodyear, Gordon D. Waiter, Neil Basu   +13 more
doaj   +1 more source

Frequency of central sensitization and nociplastic pain in patients with plantar fasciitis

International Orthopaedics
Abstract Purpose If the pain persists for a long time in the treatment of plantar fasciitis (PF) or if there is no response to treatment, central sensitization (CS) may develop and the pain may transform into nociplastic pain (NP). This study aimed to evaluate the frequency of CS and NP in patients with PF.
Demir Karakılıç, Gülseren, Melek Aykut Selçuk, Melek, Öztürk, Erhan Arif   +2 more
openaire   +2 more sources

Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure

Journal of Pain Research, 2020
Elzbieta Skorupska,1 Marta Jokiel,1,2 Michał Rychlik,3 Rafał Łochowski,4 Małgorzata Kotwicka5 1Department of Physiotherapy, Poznan University of Medical Sciences, Poznan, Poland; 2Department of Orthopedics, Traumatology and Hand Surgery Poznan University
Skorupska E, Jokiel M, Rychlik M, Łochowski R, Kotwicka M   +4 more
doaj  

Neuropathic and nociplastic pain profiles are common in adult chronic nonbacterial osteitis (CNO) [PDF]

Chronic nonbacterial osteitis (CNO) is a rare musculoskeletal disease causing chronic bone pain. It is known that chronic musculoskeletal pain may involve other mechanisms than nociceptive pain only.
Winter, E.M., Flendrie, M., Appelman-Dijkstra, N.M., Niesters, M., Dekkers, O.M., Leerling, A.T., Tel, M.   +6 more
core   +1 more source

Pain sensitisation and joint inflammation in patients with active rheumatoid arthritis

RMD Open
Introduction Despite better therapies and strategies, many people with rheumatoid arthritis (RA) have persistent pain, often from abnormal pain processing, now termed nociplastic pain.
Sam Norton, Bruce W Kirkham, James Galloway, Khaldoun Chaabo, Toby Garrood, Zoe Rutter-Locher, Estee Chan, Alex Vincent   +7 more
doaj   +1 more source

Contextualization of the concept of nociplastic pain in irritable bowel syndrome

Revista Española de Enfermedades Digestivas
The objective of this letter to the editor is to contextualize the concept of "nociplastic pain" in functional digestive disorders, especially in irritable bowel syndrome (IBS); and try to differentiate it from the term central sensitization, increasingly used in the literature, and with notable relevance in the pathophysiology of IBS.
Antonio, Alcántara Montero, Sandra Raquel, Pacheco de Vasconcelos, Alfonso, Castro Arias   +2 more
openaire   +2 more sources

Brain sensory network activity underlies reduced nociceptive initiated and nociplastic pain via acupuncture in fibromyalgia

Communications Medicine
Background Chronic pain may involve both nociceptive pain driven by peripheral tissue damage and nociplastic pain reflecting central nervous system dysregulation, as in fibromyalgia.
Apeksha Sridhar, Ishtiaq Mawla, Eric Ichesco, Brock Pluimer, Steven E. Harte, Robert Edwards, Vitaly Napadow, Richard E. Harris   +7 more
doaj   +1 more source

Could painful temporomandibular disorders be nociplastic in nature? A critical review and new proposal

Acta Odontologica Scandinavica
Classification of temporomandibular disorders (TMD) and, indeed, all types of orofacial pains has significantly progressed in the last decade based on international consensus work and operationalized clustering of signs and symptoms.
Peter Svensson
doaj   +1 more source

Psychometric evaluation and discriminative validity of the Short-Form Brief Pain Inventory across nociceptive, neuropathic, and nociplastic pain mechanisms [PDF]

The measurement performance of the Short-Form Brief Pain Inventory (BPI-SF) across IASP-recognized pain mechanisms remains unclear. We evaluated the reliability and structural validity of the BPI-SF across clinician-assigned predominant nociceptive ...
Kumbhare, Dinesh, Steen, Jeremy P., Simpson, Robert, Dilipkumar, Joana, Johnson, Sindhu R., Furlan, Andrea D., Cho, Rosalind S., Jaiswal, Kishore S.   +7 more
core   +1 more source

Microglial Activation in Nociplastic Pain: From Preclinical Models to PET Neuroimaging and Implications for Targeted Therapeutic Strategies

Nociplastic pain has recently been introduced as a third entity for identifying patients suffering from chronic pain that arises from altered nociception, without evidence of peripheral nociceptors activation or alterations of the somatosensory system ...
Marzia Malcangio, Lynda Zeboudj, Flaminia Coluzzi, Maria Sole Scerpa, Anna Giorgio, Rocco, Monica, Scerpa, Maria Sole, Malcangio, Marzia, Zeboudj, Lynda, Coluzzi, Flaminia, Monica Rocco, De Blasi, Roberto Alberto, Roberto Alberto De Blasi, Giorgio, Anna   +13 more
core   +1 more source