Results 1 to 10 of about 2,676 (127)

Chronic overlapping pain conditions and nociplastic pain [PDF]

HGG Advances
Summary: Chronic overlapping pain conditions (COPCs) are a subset of chronic pain conditions commonly comorbid with one another and more prevalent in women and individuals assigned female at birth (AFAB).
Keira J.A. Johnston, Rebecca Signer, Laura M. Huckins   +2 more
doaj   +4 more sources

The Classification of Suspected Predominant Nociplastic Pain in People with Moderate and Severe Haemophilia: A Secondary Exploratory Study

Biomedicines, 2023
In people with haemophilia (PwH), joint pain is a major comorbidity that is often overlooked and under-treated. It is believed that, to ensure the most successful outcome, pain management should be tailored to the predominant pain phenotype (i.e ...
Anthe Foubert, Nathalie Anne Roussel, Valérie-Anne Chantrain, Philip Maes, Lies Durnez, Sébastien Lobet, Catherine Lambert, Cédric Hermans, Mira Meeus   +8 more
doaj   +3 more sources

Carpal Tunnel Syndrome: Neuropathic Pain Associated or Not with a Nociplastic Condition

Biomedicines, 2023
Carpal tunnel syndrome (CTS) has been traditionally classified as primarily a neuropathic condition with or without pain. Precision medicine refers to an evidence-based method of grouping patients based on their susceptibility to biology, prognosis of a ...
César Fernández-de-las-Peñas, Stella Fuensalida-Novo, Jo Nijs, Annalie Basson, Gustavo Plaza-Manzano, Juan A. Valera-Calero, Lars Arendt-Nielsen, Ana I. de-la-Llave-Rincón   +7 more
doaj   +3 more sources

The method simulating spontaneous pain in patients with nociplastic pain using rats with fibromyalgia-like condition

MethodsX, 2020
The method shown in this article simulates spontaneous pain in patients with nociplastic pain using rats; the measurement with this method could be related to better translation of analgesic efficacies of therapeutic compounds between rats and humans ...
Shigeharu Tanei, Machiko Miwa, Miku Yoshida, Reina Miura, Yukinori Nagakura   +4 more
doaj   +3 more sources

Breaking the medication overuse headache cycle: from nociplastic pain mechanisms to patient-centered interventions — the Junior Editorial Board vision [PDF]

The Journal of Headache and Pain
Background Medication-overuse headache (MOH) is a prevalent and disabling secondary headache disorder that arises in individuals with a pre-existing primary headache as a consequence of regular overuse of acute medications.
Roberta Messina, Matteo Castaldo, Woo-Seok Ha, Alejandro Labastida-Ramirez, Sophie Merve Yener, Agnese Onofri, Eloisa Rubio-Beltran, Gabriele Sebastianelli, Doga Vuralli, William Wells-Gatnik, Paolo Martelletti   +10 more
doaj   +2 more sources

Central Sensitization and Nociplastic Pain: Shared Mechanisms in Fibromyalgia, Osteoarthritis, and Inflammatory Arthritis [PDF]

Journal of Pain Research
Fedir Volodymyrovych Hladkykh,1,2 Tetiana Ivanivna Liadova,3 Mariia Serhiivna Matvieienko,1 Roman Komorovsky,4 Svitlana Smiyan,4 Volodymyr Student5,6 1Department of General Surgery, Anesthesiology and Palliative Care, School of Medicine, V. N.
Hladkykh FV, Liadova TI, Matvieienko MS, Komorovsky R, Smiyan S, Student V   +5 more
doaj   +2 more sources

Physician-assigned Diagnosis Versus Questionnaire-based Measures in Individuals with Nociceptive, Neuropathic, and Nociplastic Pain: A Mechanism-based Characterization of Chronic Pain Patients [PDF]

Rambam Maimonides Medical Journal
Background: The International Association for the Study of Pain (IASP) has defined three mechanisms for chronic pain: nociceptive, neuropathic, and nociplastic.
Netanel Kamel, Tseela Hoffman, Mary Haddad, Amir Minerbi   +3 more
doaj   +2 more sources

Brain sensory network activity underlies reduced nociceptive initiated and nociplastic pain via acupuncture in fibromyalgia [PDF]

Communications Medicine
Background Chronic pain may involve both nociceptive pain driven by peripheral tissue damage and nociplastic pain reflecting central nervous system dysregulation, as in fibromyalgia.
Apeksha Sridhar, Ishtiaq Mawla, Eric Ichesco, Brock Pluimer, Steven E. Harte, Robert Edwards, Vitaly Napadow, Richard E. Harris   +7 more
doaj   +2 more sources

The posterior capsular central amygdala showing synaptic coactivation with nociplastic pain-associated parabrachial neurons in mice [PDF]

iScience
Summary: Projections from the external lateral parabrachial nucleus (elPB) to the central amygdala (CeA) are a key pathway for nociceptive signals and play a crucial role in establishing nociplastic pain sensitization, a state of heightened pain without ...
Takao Okuda, Sawako Uchiyama, Naoko Sato, Yae K. Sugimura, Yukari Takahashi, Makoto Tsuda, Fusao Kato   +6 more
doaj   +2 more sources

Landau model for illustrating the learning and unlearning process of nociplastic pain [PDF]

Frontiers in Pain Research
Recent advancements in understanding the consolidation of nociplastic pain point to a complex, non-conscious learned process of threat perception. Neurobiological pain education is emerging as a promising approach to unlearn nociplastic pain, supported ...
Belén Valenzuela
doaj   +2 more sources