Results 21 to 30 of about 1,002,831 (175)

Female-Specific Mechanisms of Nociplastic Pain in Murine Model [PDF]

open access: yes, 2022
Normally resolving pain can transition into chronic nociplastic pain, which predominately affects women. To facilitate mechanistic studies on nociplastic pain, we developed a murine model in which postinjury thermal stimulation of injured area triggers ...
Hankerd, Kali
core   +3 more sources

Nociplastic pain: controversy of the concept. [PDF]

open access: yesKorean J Pain
Classically, pain can be of a nociceptive or neuropathic nature, which refers to non-neural or neural tissue lesions, respectively. Chronic pain in conditions such as migraine, fibromyalgia, and complex regional pain syndrome (CRPS), is thought to perpetuate without a noxious input.
Macionis V.
europepmc   +3 more sources

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Nociplastic pain: an introduction. [PDF]

open access: yesJ Can Chiropr Assoc
Chronic pain is common in chiropractic practice and often presents without clear evidence of tissue injury. Nociplastic pain is a recently defined concept that highlights altered nociceptive processing within the nervous system. This newer understanding of pain provides insight into chronic conditions such as chronic back or neck pain, chronic ...
Roecker CB, Schut SM.
europepmc   +2 more sources

Pregabalin attenuates long-lasting post-inflammatory nociplastic mechanical sensitization in mice

open access: yesNeurobiology of Pain, 2023
Nociplastic pain, the most recently proposed mechanistic descriptor of chronic pain, is the pain resulting from an altered nociceptive system and network without clear evidence of nociceptor activation, injury or disease in the somatosensory system.
Manami Yajima   +3 more
doaj   +1 more source

327 Nociplastic pain and early discontinuation of aromatase inhibitor therapy in breast cancer patients over age 65

open access: yesJournal of Clinical and Translational Science, 2022
OBJECTIVES/GOALS: Side effects are why up to 50% of women with hormone-positive breast cancer prematurely discontinue aromatase inhibitor (AI) therapy.
Elizabeth Joyce   +2 more
doaj   +1 more source

Nociplastic pain

open access: yesAnnals of Clinical Neurophysiology, 2023
Nociplastic pain refers to pain arising from altered nociception without evidence of tissue or somatosensory damage. It encompasses various clinical conditions with shared neurophysiological mechanisms involving different organ systems. Nociplastic pain can occur independently or alongside chronic pain conditions with a nociceptive or neuropathic ...
openaire   +1 more source

MATLAB Analysis of SP Test Results—An Unusual Parasympathetic Nervous System Activity in Low Back Leg Pain: A Case Report

open access: yesApplied Sciences, 2022
The Skorupska Protocol (SP) test is a new validated tool used to confirm nociplastic pain related to muscles based on a pathological autonomic nervous system (ANS) activity due to muscle nociceptive noxious stimulation analyzed automatically.
Elzbieta Skorupska   +8 more
doaj   +1 more source

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