Adapting Tension-Type Headache to the International Association for the Study of Pain (IASP) Taxonomy: A Conceptual Proposal [PDF]
BiomedicinesTension-type headache (TTH) is a primary headache characterized by treatment effect heterogeneity, possibly reflecting variations in underlying pain mechanisms.
Margarita Cigarán-Mendez +6 more
doaj +2 more sources
Proposal to refine the mechanistic classification of chronic pain and corresponding clinical symptomatology [PDF]
Frontiers in Pain ResearchThe management and treatment of patients suffering from chronic pain must be based on a precise understanding of the pathophysiological mechanisms underlying the syndrome.
Jean-Pascal Lefaucheur +1 more
doaj +2 more sources
Mixed pain: has pain medicine overlooked Its most common phenotype for over 20 years? A perspective on mechanistic interaction, the nociplastic paradox, and the future of pain classification [PDF]
Frontiers in MedicinePain medicine has progressively evolved from a binary classification of nociceptive and neuropathic pain toward a broader mechanistic framework that now includes nociplastic pain.
Rainer Freynhagen +2 more
doaj +2 more sources
Carpal Tunnel Syndrome: Neuropathic Pain Associated or Not with a Nociplastic Condition
Biomedicines, 2023 Carpal tunnel syndrome (CTS) has been traditionally classified as primarily a neuropathic condition with or without pain. Precision medicine refers to an evidence-based method of grouping patients based on their susceptibility to biology, prognosis of a ...
Juan Antonio Valera-Calero +2 more
exaly +3 more sources
Biomedicines, 2023 In people with haemophilia (PwH), joint pain is a major comorbidity that is often overlooked and under-treated. It is believed that, to ensure the most successful outcome, pain management should be tailored to the predominant pain phenotype (i.e ...
Cedric Hermans +2 more
exaly +3 more sources
MethodsX, 2020 The method shown in this article simulates spontaneous pain in patients with nociplastic pain using rats; the measurement with this method could be related to better translation of analgesic efficacies of therapeutic compounds between rats and humans ...
Yukinori Nagakura
exaly +3 more sources
Chronic overlapping pain conditions and nociplastic pain
Human Genetics and Genomics AdvancesSummary: Chronic overlapping pain conditions (COPCs) are a subset of chronic pain conditions commonly comorbid with one another and more prevalent in women and individuals assigned female at birth (AFAB).
Rebecca Signer +2 more
exaly +3 more sources
Physician-assigned Diagnosis Versus Questionnaire-based Measures in Individuals with Nociceptive, Neuropathic, and Nociplastic Pain: A Mechanism-based Characterization of Chronic Pain Patients [PDF]
Rambam Maimonides Medical JournalBackground: The International Association for the Study of Pain (IASP) has defined three mechanisms for chronic pain: nociceptive, neuropathic, and nociplastic.
Netanel Kamel +3 more
doaj +2 more sources
Phenotyping of isolated mesh associated pain secondary to continence mesh device insertion [PDF]
Frontiers in Pain ResearchIntroductionIsolated Mesh associated Pain Syndrome (I-MAPS) is the most common complication of continence mesh devices. The pain mechanism involved remains unknown.
Hawra Badri +10 more
doaj +2 more sources
Pharmacologic Management of Pain in Children: Balancing Evidence, Safety, and Clinical Challenges [PDF]
ChildrenPain in children remains frequently underrecognized and undertreated despite significant advances in pediatric analgesia. The pharmacologic management of pediatric pain is challenging due to developmental differences in pharmacokinetics and ...
Gianmarco Marcianò +10 more
doaj +2 more sources