Results 21 to 30 of about 3,343 (187)
Implication of the Nociplastic Features for Clinical Diagnosis of Fibromyalgia: Development of the Preliminary Nociplastic‐Based Fibromyalgia Features (NFF) Tool [PDF]
ACR Open Rheumatology, 2022 Objective Nociplastic concept incorporates a broad continuum of pain phenotypes shared with clinical peculiarity. This study aimed to develop and validate a diagnostic tool, the preliminary Nociplastic‐based Fibromyalgia Features (NFF), to detect ...
Banafsheh Ghavidel‐Parsa +3 more
doaj +3 more sources
Female-Specific Mechanisms of Nociplastic Pain in Murine Model [PDF]
, 2022 Normally resolving pain can transition into chronic nociplastic pain, which predominately affects women. To facilitate mechanistic studies on nociplastic pain, we developed a murine model in which postinjury thermal stimulation of injured area triggers ...
Hankerd, Kali
core +3 more sources
South African Medical Journal, 2023 Healthcare providers face the challenging task of managing patients who suffer from chronic nociplastic pain conditions. Pain is a multidimensional experience, and the current approach to managing people in chronic pain often fails to meet the needs
J Van Der Walt, R Parker
doaj +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Parabrachial Calca neurons drive nociplasticity
Cell Reports, 2023 ABSTRACT Pain that persists beyond the time required for tissue healing and pain that arises in the absence of tissue injury are poorly understood phenomena mediated by plasticity within the central nervous system. The parabrachial nucleus (PBN) is a hub that relays aversive sensory information and appears to play a ...
Logan F. Condon +6 more
openaire +4 more sources
Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: Side effects are why up to 50% of women with hormone-positive breast cancer prematurely discontinue aromatase inhibitor (AI) therapy.
Elizabeth Joyce +2 more
doaj +1 more source
Annals of Clinical Neurophysiology, 2023 Nociplastic pain refers to pain arising from altered nociception without evidence of tissue or somatosensory damage. It encompasses various clinical conditions with shared neurophysiological mechanisms involving different organ systems. Nociplastic pain can occur independently or alongside chronic pain conditions with a nociceptive or neuropathic ...
openaire +1 more source
Applied Sciences, 2022 The Skorupska Protocol (SP) test is a new validated tool used to confirm nociplastic pain related to muscles based on a pathological autonomic nervous system (ANS) activity due to muscle nociceptive noxious stimulation analyzed automatically.
Elzbieta Skorupska +8 more
doaj +1 more source
Journal of Pain Research, 2023 Don Daniel Ocay,1– 3 Brendan D Ross,4 Lorenzo Moscaritolo,3 Nabeel Ahmed,4 Jean A Ouellet,2,5– 7 Catherine E Ferland,1– 3,6– 8,* Pablo M Ingelmo3,6– 8,* 1Department of Experimental Surgery, McGill University, Montreal, QC, Canada; 2Department of ...
Ocay DD +6 more
doaj
Chronic primary musculoskeletal pain: a new concept of nonstructural regional pain
PAIN Reports, 2022 . The concept that a regional musculoskeletal pain may occur in the absence of identifiable tissue abnormality may be puzzling. Previously these regional complaints were generally categorized as myofascial pain syndromes, or prior to the formalization of
Mary-Ann Fitzcharles +5 more
doaj +1 more source