Results 71 to 80 of about 51,241 (256)

Immunization for complex network based on the effective degree of vertex

, 2011
The basic idea of many effective immunization strategies is first to rank the importance of vertices according to the degrees of vertices and then remove the vertices from highest importance to lowest until the network becomes disconnected.
Barabási A.-L., Boguñá M., Diekmann O., Hu K., KE HU, Li Y., Milo R., Moreno Y., Yan G., YI TANG, Zhou T.   +10 more
core   +1 more source

Critical role for prokineticin 2 in CNS autoimmunity [PDF]

, 2015
Objective: To investigate the potential role of prokineticin 2 (PK2), a bioactive peptide involved in multiple biological functions including immune modulation, in CNS autoimmune demyelinating disease.
ABOU HAMDAN M, BALBONI, GIANFRANCO, CONGIU, CENZO, COSTANZA M, DI DARIO M, FARINA C, FONTANA E, LATTANZI R, MARTINELLI V, MUSIO S, NEGRI L, ONNIS, VALENTINA, PEDOTTI R., POLIANI PL, RADAELLI M, SALVADORI S, STEINMAN L   +16 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Transdermal influenza immunization with vaccine-coated microneedle arrays.

PLoS ONE, 2009
BackgroundInfluenza is a contagious disease caused by a pathogenic virus, with outbreaks all over the world and thousands of hospitalizations and deaths every year.
Dimitrios G Koutsonanos, Maria del Pilar Martin, Vladimir G Zarnitsyn, Sean P Sullivan, Richard W Compans, Mark R Prausnitz, Ioanna Skountzou   +6 more
doaj   +1 more source

Staphylococcus aureus Protection-Related Type 3 Cell-Mediated Immune Response Elicited by Recombinant Proteins and GM-CSF DNA Vaccine

Vaccines, 2021
Staphylococcus aureus mastitis remains a major challenge for dairy farming. Here, 24 mice were immunized and divided into four groups: G1: control; G2: Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) DNA vaccine; G3: F0F1 ATP synthase subunit α
Kamila R. Santos, Fernando N. Souza, Eduardo M. Ramos-Sanchez, Camila F. Batista, Luiza C. Reis, Wesley F. Fotoran, Marcos B. Heinemann, Hiro Goto, Magnus Gidlund, Adriano F. Cunha, Angélica Rosa Faria, Hélida M. Andrade, Andrey P. Lage, Mônica M. O. P. Cerqueira, Alice M. M. P. Della Libera   +14 more
doaj   +1 more source

Optimal percolation on multiplex networks

, 2017
Optimal percolation is the problem of finding the minimal set of nodes such that if the members of this set are removed from a network, the network is fragmented into non-extensive disconnected clusters.
Faqeeh, Ali, Osat, Saeed, Radicchi, Filippo   +2 more
core   +2 more sources

Benchmarking Measures of Network Influence [PDF]

, 2016
Identifying key agents for the transmission of diseases (ideas, technology, etc.) across social networks has predominantly relied on measures of centrality on a static base network or a temporally flattened graph of agent interactions.
Bramson, Aaron, Vandermarliere, Benjamin
core   +3 more sources

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Immunization coverage, knowledge, satisfaction, and associated factors of non-National Immunization Program vaccines among migrant and left-behind families in China: evidence from Zhejiang and Henan provinces

Infectious Diseases of Poverty, 2023
Background Migrant and left-behind families are vulnerable in health services utilization, but little is known about their disparities in immunization of non-National Immunization Program (NIP) vaccines.
Yaguan Zhou, Duanhui Li, Yuan Cao, Fenhua Lai, Yu Wang, Qian Long, Zifan Zhang, Chuanbo An, Xiaolin Xu   +8 more
doaj   +1 more source

Epidemic spreading and immunization strategy in multiplex networks

, 2015
A more connected world has brought major consequences such as facilitate the spread of diseases all over the world to quickly become epidemics, reason why researchers are concentrated in modeling the propagation of epidemics and outbreaks in Multilayer ...
Braunstein, Lidia A., Buono, Camila, Zuzek, Lucila G. Alvarez   +2 more
core   +1 more source