Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors. [PDF]
J Mol Biol, 2009 Protein phosphatase 1 occurs in all tissues and regulates many pathways, ranging from cell-cycle progression to carbohydrate metabolism. Many naturally occurring, molecular toxins modulate PP1 activity, though the exact mechanism of this differential regulation is not understood. A detailed elucidation of these interactions is crucial for understanding
Kelker MS, Page R, Peti W.
europepmc +4 more sources
Evaluation of Carbonized Corncobs for Removal of Microcystins and Nodularin-R from Water
SeparationsMicrocystins (MCs) and nodularins (NODs) are cyanotoxins that can be found in water bodies during cyanobacterial harmful algal blooms (cyanoHABs). Consumption of water contaminated with cyanotoxins leads to health risks for humans and animals.
Hasaruwani S. Kiridena +5 more
doaj +2 more sources
A 15-min non-competitive homogeneous assay for microcystin and nodularin based on time-resolved Förster resonance energy transfer (TR-FRET). [PDF]
Anal Bioanal Chem, 2021 Simple and rapid methods are required for screening and analysis of water samples to detect cyanobacterial cyclic peptide hepatotoxins: microcystin/nodularin.
Akter S, Lamminmäki U.
europepmc +3 more sources
A Protein-Centric Mass Spectrometry Approach for Species Identification within Harmful Algal Blooms. [PDF]
J Am Chem SocHarmful algal blooms present severe environmental threats, impacting water quality, aquatic ecosystems, and human health. The frequency and intensity of these blooms are rising, largely driven by global warming and changing climatic conditions.
Sound JK +4 more
europepmc +3 more sources
Occurrence and Diversity of Cyanotoxins and Retinoid Compounds in Antarctic Microbial Mats: Evidence From James Ross Island. [PDF]
Environ Microbiol RepOccurrence and distribution of cyanotoxins and retinoids across different Antarctic ecosystems at James Ross Island. These ecosystems harbour diverse microbial communities dominated by autotrophic cyanobacteria and algae, which can produce hazardous compounds for animals.
Sehnal L +5 more
europepmc +2 more sources
Shipin gongye ke-ji, 2022 A method was developed for the determination of nodularin (NOD) in algae-based health food by ultra-performance liquid chromatography-triple quadrupole tandem mass spectrometry (UPLC-MS/MS). The analytes were extracted from algae-based health food powder
Shuo LI, Li LI
doaj +1 more source
Using stable isotope analysis to determine the contribution of naturally occurring pond biota and supplementary feed to the diet of farmed Australian freshwater crayfish, redclaw () [PDF]
, 2015 Nutritional requirements of redclaw (Cherax quadricarinatus) farmed in Australia are poorly understood and little is known on what is actively being consumed in semi-intensive pond culture.
Joyce, Melissa K., Pirozzi, Igor
core +5 more sources
How proteins bind macrocycles [PDF]
, 2014 The potential utility of synthetic macrocycles (MCs) as drugs, particularly against low-druggability targets such as protein-protein interactions, has been widely discussed. There is little information, however, to guide the design of MCs for good target
Beglov, Dmitri +6 more
core +1 more source
Cyanobacterial Akinete Distribution, Viability, and Cyanotoxin Records in Sediment Archives from the Northern Baltic Sea [PDF]
, 2022 Cyanobacteria of the order Nostocales, including Baltic Sea bloom-forming taxa Nodularia spumigena, Aphanizomenon flosaquae, and Dolichospermum spp., produce resting stages, known as akinetes, under unfavorable conditions.
Akter Sultana +6 more
core +1 more source
Αξιολόγηση βιοχημικών δεικτών στην εκτίμηση της βιοσυσσώρευσης κυανοβακτηριακών τοξινών στο είδος Cyprinus carpio Linnaeus 1758, στη λίμνη Κάρλα [PDF]
, 2012 Σημείωση: διατίθεται συμπληρωματικό υλικό σε ξεχωριστό ...
Κλάιμπερ, Μάριος Α.
core +1 more source