Results 181 to 190 of about 4,015 (236)

Bacterial Degradation of Microcystins and Nodularin

Chemical Research in Toxicology, 2005
Microcystins and nodularins produced by cyanobacteria are potent hepatotoxins and tumor promoters. They are, respectively, cyclic heptapeptides and cyclic pentapeptides containing a characteristic beta-amino acid residue, (2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4(E ),6(E)-dienoic acid (Adda).
Susumu, Imanishi, Hajime, Kato, Masayoshi, Mizuno, Kiyomi, Tsuji, Ken-ichi, Harada   +4 more
openaire   +2 more sources

Biodegradation of microcystins and nodularin in freshwaters

Chemosphere, 2008
Microcystin-LR (MC-LR) was readily biodegraded on addition to six different water samples irrespective of their previous exposure to microcystins. Subsequent studies with water from three of these water bodies confirmed the degradation of MC-LR and also demonstrated the biodegradation of MC-LF, nodularin and mixture of microcystins and nodularin. Rates
Christine, Edwards, Douglas, Graham, Nicholas, Fowler, Linda A, Lawton   +3 more
openaire   +2 more sources

Iningainema tapete sp. nov. (Scytonemataceae, Cyanobacteria) from greenhouses in central Florida (USA) produces two types of nodularin with biosynthetic potential for microcystin-LR and anabaenopeptin production.

Harmful Algae, 2021
Iningainema is a recently described genus of heterocytous, false-branching cyanobacteria originally described from Australia. In this work, we present Iningainema tapete sp.
D. Berthold, Forrest W. Lefler, I. Huang, H. Abdulla, P. Zimba, H. D. Laughinghouse   +5 more
semanticscholar   +1 more source

Nodularin uptake by seafood during a cyanobacterial bloom

Environmental Toxicology, 2001
AbstractThe problem of blue‐green algal toxin contamination of recreational waters and drinking water catchments is well described, as is the potential contamination of associated seafood. Algal contamination of Victorian waterways is now a widespread annual occurrence and, in some regions, the intersection of blooms and commercial fishing threatens ...
P G, Van Buynder, T, Oughtred, B, Kirkby, S, Phillips, G, Eaglesham, K, Thomas, M, Burch   +6 more
openaire   +2 more sources

Cytotoxic and immunological responses of fish leukocytes to nodularin exposure in vitro

Journal of Applied Toxicology, 2021
Nodularin (NOD) is a cyclic peptide released by bloom‐forming toxic cyanobacteria Nodularia spumigena commonly occurring in brackish waters throughout the world.
A. Rymuszka, A. Sierosławska, Ł. Adaszek   +2 more
semanticscholar   +1 more source

Total Synthesis of Motuporin (Nodularin-V)

Journal of the American Chemical Society, 1999
The serine/threonine phosphatase (protein phosphatase 1 and 2A) inhibitors constitute a biologically and structurally interesting class of natural products. Among this class of inhibitors are cyclic pentapeptides (nodularins) and cyclic heptapeptides (microcystins), both of which inhibit at the nanomolar level and are the only peptide inhibitors of ...
Shawn M. Bauer, Robert W. Armstrong
openaire   +1 more source

Lymphoid depletion in two dogs with nodularin intoxication

Veterinary Record, 2011
NODULARIN-related intoxications have been described in a variety of species, including dogs (Main and others 1977, Beasley and others 1989, van Halderen and others 1995, Duy and others 2000, van Apeldoorn and others 2007, Broker and others 2010). Nodularin is a potent hepatotoxin produced by the cyanobacterium Nodularia spumigena , which can be found ...
D, Algermissen, R, Mischke, F, Seehusen, J, Göbel, A, Beineke   +4 more
openaire   +2 more sources

Toxicopathology Induced by Microcystins and Nodularin: A Histopathological Review

Journal of Environmental Science and Health, Part C, 2015
Cyanobacteria are present in all aquatic ecosystems throughout the world. They are able to produce toxic secondary metabolites, and microcystins are those most frequently found. Research has displayed a negative influence of microcystins and closely related nodularin on fish, and various histopathological alterations have been observed in many organs ...
Zorica, Svirčev, Jelena, Lujić, Zoran, Marinović, Damjana, Drobac, Nada, Tokodi, Bratislav, Stojiljković, Jussi, Meriluoto   +6 more
openaire   +2 more sources

Neither microcystin, nor nodularin, nor cylindrospermopsin directly interact with human toll-like receptors.

Chemosphere, 2021
Various stressors including temperature, environmental chemicals, and toxins can have profound impacts on immunity to pathogens. Increased eutrophication near rivers and lakes coupled with climate change are predicted to lead to increased algal blooms ...
J. Hansen, K. Loftin, Zachary Laughrey, O. Adamovsky   +3 more
semanticscholar   +1 more source

Extraction of 15 microcystins and nodularin using immunoaffinity columns

Toxicon, 2003
Microcystins (MCYSTs) were isolated from surface water using reusable immunoaffinity columns. Individual MCYST were determined by high performance liquid chromatography equipped with a photo-diode array detector (HPLC-PDA, 200-300 nm). Subsequent analysis of the samples by liquid chromatography-electrospray ionization mass spectrometry (LC-ESMS ...
Rocio, Aranda-Rodriguez, Cariton, Kubwabo, Frank M, Benoit   +2 more
openaire   +2 more sources