Results 171 to 180 of about 3,166 (211)

Lymphoid depletion in two dogs with nodularin intoxication

Veterinary Record, 2011
NODULARIN-related intoxications have been described in a variety of species, including dogs (Main and others 1977, Beasley and others 1989, van Halderen and others 1995, Duy and others 2000, van Apeldoorn and others 2007, Broker and others 2010). Nodularin is a potent hepatotoxin produced by the cyanobacterium Nodularia spumigena , which can be found ...
D, Algermissen, R, Mischke, F, Seehusen, J, Göbel, A, Beineke   +4 more
openaire   +2 more sources

Apoptotic responses of Carassius auratus lymphocytes to nodularin exposure in vitro

Fish and Shellfish Immunology, 2012
Nodularin, a metabolite of Nodularin spumigena, is widely detected in water blooms worldwide and causes serious negative effects on fish. The apoptosis-related cytotoxic effects and mechanisms of nodularin on Carassius auratus lymphocytes were investigated.
Hangjun Zhang
exaly   +3 more sources

Toxicopathology Induced by Microcystins and Nodularin: A Histopathological Review

Journal of Environmental Science and Health, Part C, 2015
Cyanobacteria are present in all aquatic ecosystems throughout the world. They are able to produce toxic secondary metabolites, and microcystins are those most frequently found. Research has displayed a negative influence of microcystins and closely related nodularin on fish, and various histopathological alterations have been observed in many organs ...
Zorica, Svirčev, Jelena, Lujić, Zoran, Marinović, Damjana, Drobac, Nada, Tokodi, Bratislav, Stojiljković, Jussi, Meriluoto   +6 more
openaire   +2 more sources

Extraction of 15 microcystins and nodularin using immunoaffinity columns

Toxicon, 2003
Microcystins (MCYSTs) were isolated from surface water using reusable immunoaffinity columns. Individual MCYST were determined by high performance liquid chromatography equipped with a photo-diode array detector (HPLC-PDA, 200-300 nm). Subsequent analysis of the samples by liquid chromatography-electrospray ionization mass spectrometry (LC-ESMS ...
Rocio, Aranda-Rodriguez, Cariton, Kubwabo, Frank M, Benoit   +2 more
openaire   +2 more sources

Deposit-feeders accumulate the cyanobacterial toxin nodularin

Harmful Algae, 2011
Animals living in marine sediments (the second largest habitat on earth) play a major role in global biogeochemical cycling. By feeding on organic matter from settled phytoplankton blooms they produce food for higher trophic levels and nutrients that can fuel primary production.
Agnes M.L. Karlson, Raimondas Mozūraitis   +1 more
openaire   +1 more source

Comprehensive insights into the occurrence and toxicological issues of nodularins

Marine Pollution Bulletin, 2021
The occurrence of cyanobacterial toxins is being increasingly reported. Nodularins (NODs) are one of the cyanotoxins group mainly produced by Nodularia spumigena throughout the world. NODs may exert adverse effects on animal and human health, and NOD-R variant is the most widely investigated. However, research focused on them is still limited. In order
Guoliang, Chen, Linping, Wang, Mingxing, Wang, Tingzhang, Hu   +3 more
openaire   +2 more sources

New Nodularins: A General Method for Structure Assignment

The Journal of Organic Chemistry, 1994
A general method has been developed for assigning the structures of nodularin, a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor, and minor components isolated from a cultured and a bloom sample of the cyanobacterium Nodularia spumigena.
Michio Namikoshi, Byoung Wook Choi, Ryuichi Sakai, Furong Sun, Kenneth L. Rinehart, Wayne W. Carmichael, William R. Evans, Phillip Cruz, Murray H. G. Munro, John W. Blunt   +9 more
openaire   +1 more source

Hydrolysis of microcystins and nodularin by microwave radiation

Chromatographia, 1999
Microwave radiation has been successfully used for hydrolysis of the hepatotoxic cyclic peptides microcystins and nodularin. Set-up of the microwave device and the operating conditions for microwave hydrolysis were optimized. Results of the microwave hydrolysis were compared with results from conventional hydrolysis for 24 h at 110°C.
M. Reichelt, C. Hummert, B. Luckas
openaire   +1 more source

ChemInform Abstract: Total Synthesis of Motuporin (Nodularin‐V).

ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Shawn M. Bauer, Robert W. Armstrong
openaire   +1 more source

Nodularin, microcystin, and the configuration of Adda

Journal of the American Chemical Society, 1988
Kenneth L. Rinehart, Kenichi. Harada, Michio. Namikoshi, Choryu. Chen, Carl A. Harvis, Murray H. G. Munro, John W. Blunt, Paul E. Mulligan, Val R. Beasley, . et al.   +9 more
exaly   +2 more sources