Results 181 to 190 of about 3,166 (211)

Detection of nodularin in flounders and cod from the Baltic Sea

Environmental Toxicology, 2001
AbstractThe brackish water cyanobacterium Nodularia spumigena regularly forms waterblooms in the Baltic Sea. Many N. spumigena strains can produce nodularin, a hepatotoxic penta‐peptide, which has caused several animal poisonings in the Baltic Sea area.
Harri Kankaanpää, Jussi Meriluoto
exaly   +3 more sources

Production of the cyanotoxin nodularin—A multifactorial approach

Harmful Algae, 2010
Abstract Summer blooms in the Baltic Sea are dominated by the diazotrophic cyanobacteria Nodularia spumigena and Aphanizomenon sp. During the blooms, N. spumigena is concentrated to the water surface and exposed to high irradiances of both photosynthetic active radiation (PAR, 400–700 nm) and ultraviolet radiation (UVR, 280–400 nm), in addition, this
Bagmi Pattanaik, Angela Wulff, Michael Y. Roleda, Kristine Garde, Malin Mohlin   +4 more
openaire   +1 more source

Genotoxic effects of the cyanobacterial pentapeptide nodularin in HepG2 cells

Food and Chemical Toxicology, 2019
The cyanobacterial pentapeptide nodularin (NOD), mainly produced by genus Nodularia, is a potent inhibitor of protein phosphatases PP1 and PP2A, and causes animal mortality. The few studies available indicate that NOD is a potential non-genotoxic carcinogen.
A. Štern, A. Rotter, M. Novak, M. Filipič, B. Žegura   +4 more
openaire   +2 more sources

Biodegradation and sorption of nodularin (NOD) in fine-grained sediments

Chemosphere, 2008
Nodularin (NOD) is a cyclic pentapeptide hepatotoxin produced by the bloom forming cyanobacterium Nodularia spumigena. The fate of the toxin in the aquatic environment has not been fully evaluated. In the current study the changes in NOD concentration caused by biodegradation and sorption in samples from the Baltic were studied.
Anna, Toruńska, Jerzy, Bolałek, Marcin, Pliński, Hanna, Mazur-Marzec   +3 more
openaire   +2 more sources

Separation of microcystins and nodularins by ultra performance liquid chromatography

Journal of Chromatography B, 2009
Four ultra performance liquid chromatography (UPLC) columns with different reversed-phase characteristics were tested in the chromatographic separation of 10 microcystins and three nodularins, cyanobacterial peptide toxins. The columns had been designed by the manufacturer to withstand the ultra-high pressure generated by sub-2microm stationary phase ...
Lisa, Spoof, Milla-Riina, Neffling, Jussi, Meriluoto   +2 more
openaire   +2 more sources

Nodularin from benthic freshwater periphyton and implications for trophic transfer

Toxicon, 2017
In 2013 and 2015, the Pennsylvania Department of Environmental Protection conducted a survey of lotic habitats within the Susquehanna, Delaware, and Ohio River basins in Pennsylvania, USA, to screen for microcystins/nodularins (MCs/NODs) in algae communities and smallmouth bass (Micropterus dolomieu). Periphyton (68 from 41 sites), juvenile whole fish (
Amanda J. Foss, Jeffery Butt, Sarah Fuller, Kamil Cieslik, Mark T. Aubel, Tim Wertz   +5 more
openaire   +2 more sources

Cloud-point extraction of nodularin-R from natural waters

Analytica Chimica Acta, 2004
Abstract A cloud-point extraction (CPE) technique for the determination of a cyanobacterial hepatotoxin, nodularin-R, in aqueous media using a cationic surfactant, tricaprylmethylammonium chloride (Aliquat-336), was developed. Cloud-point phase separation of Aliquat-336 at ambient temperature was induced by the addition of sodium sulfate. The Aliquat-
Paul K S Lam
exaly   +4 more sources

Uptake and accumulation of dissolved, radiolabeled nodularin in Baltic Sea zooplankton

Environmental Toxicology, 2003
AbstractThe mass occurrence of toxic cyanobacteria is a recurrent phenomenon in the Baltic Sea. Grazers may obtain toxins either through ingestion or by direct exposure to dissolved toxins. Despite this, there is little knowledge about the accumulation of cyanobacterial toxins in planktonic organisms present during these blooms.
M, Karjalainen, M, Reinikainen, F, Lindvall, L, Spoof, J A O, Meriluoto   +4 more
openaire   +2 more sources

Mass spectrometric detection of nodularin and desmethylnodularin in mussels and flounders

Journal of Chromatography B, 2003
Samples of mussels and flounders from the Baltic Sea were analysed for nodularin content on two different LC-MS instruments (triple quadrupole and ion trap). The triple quadrupole instrument was well suited for the quantitative analysis. The limit of detection in the selected ion recording mode was 5 pg and in the multiple reactant monitoring mode 500 ...
Krister, Karlsson, Vesa, Sipiä, Harri, Kankaanpää, Jussi, Meriluoto   +3 more
openaire   +2 more sources

The degradation of the cyanobacterial hepatotoxin nodularin (NOD) by UV radiation

Chemosphere, 2006
This study investigates the decomposition of NOD by UV irradiation. Water solutions of pure NOD and NOD-containing Nodularia extract as well as Nodularia filaments collected on filters were exposed to UV-A, UV-B, and white fluorescent light (VIS) during 48 h experiments. In VIS, the toxin was fairly stable and only 3.8-4.6% of the original degraded. UV-
Hanna, Mazur-Marzec, Jussi, Meriluoto, Marcin, Pliński   +2 more
openaire   +2 more sources