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Solution Structure of Nodularin [PDF]
Journal of Biological Chemistry, 1996 The three-dimensional solution structure of nodularin was studied by NMR and molecular dynamics simulations. The conformation in water was determined from the distance and dihedral data by distance geometry and refined by iterative relaxation matrix analysis. The cyclic backbone adopts a well defined conformation but the remote parts of the side chains
Arto Annila +6 more
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Shipin gongye ke-ji, 2022 A method was developed for the determination of nodularin (NOD) in algae-based health food by ultra-performance liquid chromatography-triple quadrupole tandem mass spectrometry (UPLC-MS/MS). The analytes were extracted from algae-based health food powder
Shuo LI, Li LI
doaj +1 more source
Shifts in DNA yield and biological community composition in stored sediment: implications for paleogenomic studies [PDF]
Metabarcoding and Metagenomics, 2022 Lake sediments hold a wealth of information from past environments that is highly valuable for paleolimnological reconstructions. These studies increasingly apply modern molecular tools targeting sedimentary DNA (sedDNA).
Katie A. Brasell +8 more
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Congener-Independent Immunoassay for Microcystins and Nodularins [PDF]
Environmental Science & Technology, 2001 Cyanobacteria (blue-green algae) (e.g., Microcystis and Nodularia spp.) capable of producing toxic peptides are found in fresh and brackish water worldwide. These toxins include the microcystin (MC) heptapeptides (>60 congeners) and the nodularin pentapeptides (ca. 5 congeners).
Fischer, Werner Jürgen +7 more
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Microorganisms, 2022 (1) Background: Cyanobacteria produce a wide range of secondary metabolites, including tumor-promoting hepatotoxins. We recently reported evidence of an independent association between oral cyanobacteria and hepatocellular carcinoma in a U.S. population.
Brenda Y. Hernandez +6 more
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Frontiers in Microbiology, 2021 Toxin-producing cyanobacteria can be harmful to aquatic biota, although some grazers utilize them with often beneficial effects on their growth and reproduction. It is commonly assumed that gut microbiota facilitates host adaptation to the diet; however,
Elena Gorokhova +3 more
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Water, 2022 Cyanotoxins can be produced in surface waters by cyanobacterial blooms, mostly during summer and early autumn. Intoxications would result from consumption of water contaminated with the potent hepatotoxins, microcystins and nodularin.
W. H. V. Van Hassel +4 more
semanticscholar +1 more source
Toxins, 2012 Apoptotic cell death is induced in primary hepatocytes by the Ser/Thr protein phosphatase inhibiting cyanobacterial toxin nodularin after only minutes of exposure. Nodularin-induced apoptosis involves a rapid development of reactive oxygen species (ROS),
Kari E. Fladmark +4 more
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Blooms of Toxic Cyanobacterium Nodularia spumigena in Norwegian Fjords During Holocene Warm Periods
Toxins, 2020 In paleoecological studies, molecular markers are being used increasingly often to reconstruct community structures, environmental conditions and ecosystem changes.
Robert Konkel +6 more
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Frontiers in Microbiology, 2021 Cyanobacteria of the order Nostocales, including Baltic Sea bloom-forming taxa Nodularia spumigena, Aphanizomenon flosaquae, and Dolichospermum spp., produce resting stages, known as akinetes, under unfavorable conditions.
Steffaney M. Wood +6 more
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