Results 11 to 20 of about 3,166 (211)
Rapid and Highly Sensitive Non-Competitive Immunoassay for Specific Detection of Nodularin [PDF]
Microorganisms, 2017 Nodularin (NOD) is a cyclic penta-peptide hepatotoxin mainly produced by Nodularia spumigena, reported from the brackish water bodies of various parts of the world.
Sultana Akter +3 more
doaj +4 more sources
Pathway for Biodegrading Nodularin (NOD) by Sphingopyxis sp. USTB-05 [PDF]
Toxins, 2016 Nodularin (NOD) is greatly produced by Nodularia spumigena and released into the environment when toxic cyanobacterial blooms happened in natural water body, which is seriously harmful to human and animals.
Nan Feng +8 more
doaj +3 more sources
Occurrence and Diversity of Cyanotoxins and Retinoid Compounds in Antarctic Microbial Mats: Evidence From James Ross Island. [PDF]
Environ Microbiol RepOccurrence and distribution of cyanotoxins and retinoids across different Antarctic ecosystems at James Ross Island. These ecosystems harbour diverse microbial communities dominated by autotrophic cyanobacteria and algae, which can produce hazardous compounds for animals.
Sehnal L +5 more
europepmc +2 more sources
Gut Microbiomes of Marine Zooplankton: Consequences for Host Performance, the Biological Carbon Pump, and Prokaryote Biogeography. [PDF]
Environ MicrobiolExpected effects of zooplankton microbiota on the host and on the ecosystem. Stylized mesozooplankton holobiont (center) with arrows indicating respiration within the gut and export of faecal pellets and associated microbes. Orange bubbles summarise microbiome‐mediated consequences for host performance (digestive help, detoxification, vitamin ...
Calbet A.
europepmc +2 more sources
Nodularin-R Synergistically Enhances Abiraterone Against Castrate- Resistant Prostate Cancer via PPP1CA Inhibition. [PDF]
J Cell Mol MedABSTRACT Clinically, most prostate cancer (PCa) patients inevitably progress to castration‐resistant prostate cancer (CRPC) with poor prognosis after androgen deprivation therapy (ADT), including abiraterone, the drug of choice for ADT. Therefore, it is necessary to explore the resistance mechanism of abiraterone in depth.
Huang Y +8 more
europepmc +2 more sources
Solution Structure of Nodularin [PDF]
Journal of Biological Chemistry, 1996 The three-dimensional solution structure of nodularin was studied by NMR and molecular dynamics simulations. The conformation in water was determined from the distance and dihedral data by distance geometry and refined by iterative relaxation matrix analysis. The cyclic backbone adopts a well defined conformation but the remote parts of the side chains
Arto Annila +6 more
openaire +3 more sources
Congener-Independent Immunoassay for Microcystins and Nodularins [PDF]
Environmental Science & Technology, 2001 Cyanobacteria (blue-green algae) (e.g., Microcystis and Nodularia spp.) capable of producing toxic peptides are found in fresh and brackish water worldwide. These toxins include the microcystin (MC) heptapeptides (>60 congeners) and the nodularin pentapeptides (ca. 5 congeners).
Fischer, Werner Jürgen +7 more
openaire +3 more sources
Frontiers in Microbiology, 2021 Toxin-producing cyanobacteria can be harmful to aquatic biota, although some grazers utilize them with often beneficial effects on their growth and reproduction. It is commonly assumed that gut microbiota facilitates host adaptation to the diet; however,
Elena Gorokhova +3 more
doaj +1 more source
Toxins, 2012 Apoptotic cell death is induced in primary hepatocytes by the Ser/Thr protein phosphatase inhibiting cyanobacterial toxin nodularin after only minutes of exposure. Nodularin-induced apoptosis involves a rapid development of reactive oxygen species (ROS),
Kari E. Fladmark +4 more
doaj +1 more source
Biosensors, 2019 Cyanobacterial blooms cause local and global health issues by contaminating surface waters. Microcystins and nodularins are cyclic cyanobacterial peptide toxins comprising numerous natural variants.
Sultana Akter +5 more
doaj +1 more source