Toxins, 2012 Apoptotic cell death is induced in primary hepatocytes by the Ser/Thr protein phosphatase inhibiting cyanobacterial toxin nodularin after only minutes of exposure. Nodularin-induced apoptosis involves a rapid development of reactive oxygen species (ROS),
Kari E. Fladmark +4 more
doaj +2 more sources
Prediction of present and future spatial occurrence of cyanobacteria and the toxin nodularin in the Baltic Sea [PDF]
BiogeosciencesBlooms of filamentous cyanobacteria are recurrent phenomena in the brackish Baltic Sea. These blooms can contain toxin-producing strains. However, predicting and modeling the toxins spatial distribution poses great challenges.
M. Abdelgadir +4 more
doaj +2 more sources
Production of High Amounts of Hepatotoxin Nodularin and New Protease Inhibitors Pseudospumigins by the Brazilian Benthic Nostoc sp. CENA543 [PDF]
Frontiers in Microbiology, 2017 Nostoc is a cyanobacterial genus, common in soils and a prolific producer of natural products. This research project aimed to explore and characterize Brazilian cyanobacteria for new bioactive compounds.
Jouni Jokela +10 more
doaj +2 more sources
Evaluating the Potential Inhibition of PP2A by Nodularin-R Disinfection By-Products: Effect and Mechanism [PDF]
ToxinsThe secondary contamination of nodularin disinfection by-products (NOD-DBPs) is a problem worthy of attention. In this study, prototypical NOD-R-DBPs were prepared, and their toxicity was assessed using conventional protein phosphatase (PPs) inhibition ...
Mengchen Li +4 more
doaj +2 more sources
Journal of Limnology, 2015 The occurrence of cyanobacteria species Nodularia spumigena and its toxin nodularin were studied in Burdur Lake, a saline alkaline lake with endemic fauna and a Ramsar site of ornithological importance.
Fatma Sahindokuyucu Kocasari +4 more
doaj +2 more sources
Pathway for Biodegrading Nodularin (NOD) by Sphingopyxis sp. USTB-05
Toxins, 2016 Nodularin (NOD) is greatly produced by Nodularia spumigena and released into the environment when toxic cyanobacterial blooms happened in natural water body, which is seriously harmful to human and animals.
Fan Yang, Haiyang Zhang, Hai Yan
exaly +3 more sources
On the Chemistry, Toxicology and Genetics of the Cyanobacterial Toxins, Microcystin, Nodularin, Saxitoxin and Cylindrospermopsin [PDF]
Marine Drugs, 2010 The cyanobacteria or “blue-green algae”, as they are commonly termed, comprise a diverse group of oxygenic photosynthetic bacteria that inhabit a wide range of aquatic and terrestrial environments, and display incredible morphological diversity.
Leanne Pearson +4 more
doaj +5 more sources
Stability of cyanotoxins, microcystin-LR, microcystin-RR and nodularin in seawater and BG-11 medium of different salinity [PDF]
Oceanologia, 2001 Microcystins and nodularin are potent hepatotoxins produced by fresh and seawater cyanobacteria. The persistence of three hepatotoxins - microcystin-LR, microcystin-RR and nodularin - was investigated in sterile BG-11 medium of different salinity and in ...
Hanna Mazur, Marcin Pliñski
doaj +1 more source
Occurrence and Diversity of Cyanotoxins and Retinoid Compounds in Antarctic Microbial Mats: Evidence From James Ross Island. [PDF]
Environ Microbiol RepOccurrence and distribution of cyanotoxins and retinoids across different Antarctic ecosystems at James Ross Island. These ecosystems harbour diverse microbial communities dominated by autotrophic cyanobacteria and algae, which can produce hazardous compounds for animals.
Sehnal L +5 more
europepmc +2 more sources
Gut Microbiomes of Marine Zooplankton: Consequences for Host Performance, the Biological Carbon Pump, and Prokaryote Biogeography. [PDF]
Environ MicrobiolExpected effects of zooplankton microbiota on the host and on the ecosystem. Stylized mesozooplankton holobiont (center) with arrows indicating respiration within the gut and export of faecal pellets and associated microbes. Orange bubbles summarise microbiome‐mediated consequences for host performance (digestive help, detoxification, vitamin ...
Calbet A.
europepmc +2 more sources