Effect of nodularin on the expression of glutathione S-transferase placental form and proliferating cell nuclear antigen in N-nitrosodiethylamine initiated hepatocarcinogenesis in the male Fischer 344 rat [PDF]
, 1999 The tumor-promoting effect of nodularin during carcinogenesis was investigated. Male Fischer 344 rats were injected with nodularin for 10 weeks from week 3 after N-nitrosodiethylamine initiation without partial hepatectomy.
Sang Chul Park +6 more
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Oral exposure to environmental cyanobacteria toxins: Implications for cancer risk
Environment International, 2021 Background: Areca nut/betel quid (AN/BQ) chewing, a prevalent practice in parts of the Pacific and Asia, is an independent cause of cancers of the oral cavity and esophagus and may be linked to liver cancer.
Brenda Y. Hernandez +3 more
doaj +1 more source
Selective left-lobe atrophy by nodularin treatment accompanied by reduced protein phosphatase 1/2A and increased peroxisome proliferation in rat liver. [PDF]
, 2001 The effect of nodularin on selective atrophy of left lobes in the liver was investigated in F344 rats. Nodularin was injected for 10 weeks from the third week of initiation with saline or N-nitrosodiethylamine (DEN), grouped as S/N and D/N, respectively.
Kwak, CS +17 more
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Impact of Environmental Factors on the Regulation of Cyanotoxin Production
Toxins, 2014 Cyanobacteria are capable of thriving in almost all environments. Recent changes in climatic conditions due to increased human activities favor the occurrence and severity of harmful cyanobacterial bloom all over the world. Knowledge of the regulation of
Thangavelu Boopathi, Jang-Seu Ki
doaj +1 more source
In vivo assessment of nodularin-induced hepatotoxicity in the rat using magnetic resonance techniques (MRI, MRS and EPR oximetry) [PDF]
, 2002 Acute nodularin-induced hepatotoxicity was assessed in vivo, in rats using magnetic resonance (MR) techniques, including MR imaging (MRI), MR spectroscopy (MRS), and electron paramagnetic resonance (EPR) oximetry.
Khan, Nadeem +4 more
core +1 more source
Accumulation of nodularin in New Zealand shortfin eel (Anguilla australis): potential consequences for human consumption [PDF]
, 2017 The native Anguilla australis (shortfin eel) is a culturally significant species for indigenous Māori populations of New Zealand. At Lake Forsyth/Te Wairewa (Canterbury), local Māori have depended on A.
J Puddick (3196746) +2 more
core +1 more source
Toxins, 2021 Currently, studies worldwide have comprehensively recognized the importance of Sphingomonadaceae bacteria and the mlrCABD gene cluster in microcystin (MC) degradation. However, knowledge about their degradation of nodularin (NOD) is still unclear.
Mengxuan Yuan +5 more
doaj +1 more source
Rapid purification of the peptide toxins microcystin-LR and nodularin [PDF]
FEMS Microbiology Letters, 1990 An isolation procedure was developed to provide within one day microcystin-LR, a cyclic heptapeptide toxin from Microcystis aeruginosa PCC 7806. After ODS (octadecylsilyl) solid phase extraction, the crude toxin fraction was chromatographed using a strong anion exchange column. The toxin was eluted with 0.02 M ammonium bicarbonate.
C, Martin +4 more
openaire +2 more sources
Toxicon: X, 2020 Numerous toxin-producing harmful algal (HAB) species occur in Florida's coastal waters. Exposure to these toxins has been shown to have sublethal effects in sea turtles.
Justin R. Perrault +5 more
doaj +1 more source
Marked inhibition of testosterone biosynthesis by the hepatotoxin nodularin due to apoptosis of Leydig cells. [PDF]
, 2002 We previously observed that the serum testosterone level was greatly reduced in the course of diethylnitrosamine-nodularin-induced hepatocarcinogenesis in Fischer 344 male rats (Lim et al., Gastroenterological Carcinogenesis, 1999).
Sohn, SH, Lim, IK, Song, KY, Park, TJ
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