Results 31 to 40 of about 1,263,529 (296)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
AIP Advances, 2022 In order to explore the rising and diffusing path of an underwater thermal jet and the temperature variation of each water layer in the typical ocean thermohaline stratified environment, a three-dimensional mass-heat transport model of the thermal jet in
Feiyang Luo +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Current Biology, 2019 Noise pollution has spread over the entire globe: from the initial rumble in the Stone age, the invention of gun powder, and a steady rise during the industrial revolution, to a global acceleration in the second half of the 20th century. Hans Slabbekoorn highlights what we know about the impact of this acoustic climate change, on humans and animals ...
openaire +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Bearing Health Evaluation Model using Segmentive Technique and Cosine KNN in Different Loading Situations [PDF]
ITM Web of ConferencesBearing faults are a common cause of machinery failure, and bearing vibration analysis is critical in preventing any unacceptable consequences of such failures.
Yap J.S., Lim M.H., Leong M. Salman
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Enhanced Bearing Fault Analysis under Inconstant Loads Conditions by Cosine Weighted K-Nearest Neighbours Model [PDF]
ITM Web of ConferencesBearing faults often lead to machinery failures, underscoring the importance of analyzing bearing vibrations to avert undesirable consequences. Leveraging Artificial Intelligence (AI) in this context benefits from the strides in intelligent data ...
Yap J.S., Lim M.H., Leong M. Salman
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Review of Underground Storage Tank Condition Monitoring Techniques
MATEC Web of Conferences, 2019 This article aims to provide a comprehensive review on the condition monitoring techniques of underground storage tanks (UST). Generally, the UST has long been a favourite toxic substance reservation apparatus, thanks to its large capacity and minimum ...
Ching Sheng Ooi +4 more
doaj +1 more source