Results 51 to 60 of about 5,592,166 (367)

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Numerical modeling techniques for noise emission of free railway wheels

Railway Engineering Science
In this article, we consider the numerical prediction of the noise emission from a wheelset in laboratory conditions. We focus on the fluid–structure interaction leading to sound emission in the fluid domain by analyzing three different methods to ...
Linus Taenzer, Urs Pachale, Bart Van Damme, Andrea Bergamini, Domenico Tallarico   +4 more
doaj   +1 more source

Geometric line-of-sight guidance law with exponential switching sliding mode control for marine vehicles’ path following

Frontiers in Robotics and AI
Marine vehicle guidance and control technology serves as the core support for advancing marine development and enabling scientific exploration. Its accuracy, autonomy, and environmental adaptability directly determine a vehicle’s mission effectiveness in
Chengren Yuan, Chengren Yuan, Changgeng Shuai, Changgeng Shuai, Zhanshuo Zhang, Zhanshuo Zhang, Buyun Li, Buyun Li, Yuqiang Cheng, Yuqiang Cheng, Jianguo Ma, Jianguo Ma   +11 more
doaj   +1 more source

Automated Valve Fault Detection Based on Acoustic Emission Parameters and Artificial Neural Network

MATEC Web of Conferences, 2019
Reciprocating compressor is one of the most popular classes of machines use with wide applications in the industry. However, valve failures in this machine often results unplanned shutdown. Therefore, the effective valve fault detection technique is very
Salah M. Ali Al-Obaidi, Hui K.H., Hee L.M., Leong M. Salman, Mahdi Ali Abdul-Hussain, Abdelrhman Ahmed M., Ali YH   +6 more
doaj   +1 more source

Bearing Health Evaluation Model using Segmentive Technique and Cosine KNN in Different Loading Situations [PDF]

ITM Web of Conferences
Bearing faults are a common cause of machinery failure, and bearing vibration analysis is critical in preventing any unacceptable consequences of such failures.
Yap J.S., Lim M.H., Leong M. Salman
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Enhanced Bearing Fault Analysis under Inconstant Loads Conditions by Cosine Weighted K-Nearest Neighbours Model [PDF]

ITM Web of Conferences
Bearing faults often lead to machinery failures, underscoring the importance of analyzing bearing vibrations to avert undesirable consequences. Leveraging Artificial Intelligence (AI) in this context benefits from the strides in intelligent data ...
Yap J.S., Lim M.H., Leong M. Salman
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

The Modeling Method for Vibration Characteristics Analysis of Composite-Laminated Rotationally Stiffened Plate

Shock and Vibration
The composite-laminated rotationally stiffened plate is widely applied in aviation, aerospace, ship, machinery, and other fields. For structural design and optimization, to investigate the vibration characteristics is important. In this paper, a modeling
Hong Zhang, Yiqun Ding, Lin He, Changgeng Shuai, Chao Jiang   +4 more
doaj   +1 more source

Anisotropic noise [PDF]

ACM Transactions on Graphics, 2008
Programmable graphics hardware makes it possible to generate procedural noise textures on the fly for interactive rendering. However, filtering and antialiasing procedural noise involves a tradeoff between aliasing artifacts and loss of detail. In this paper we present a technique, targeted at interactive applications, that provides high-quality ...
Goldberg, Alexander, Zwicker, Matthias, Durand, Fredo   +2 more
openaire   +3 more sources