Results 161 to 170 of about 42,527 (280)

Exosomal Gene Biomarkers in Osteosarcoma: Mifepristone as a Targeted Therapeutic Revealed by Multi‐Omics Analysis

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
Integrated osteosarcoma and exosome gene datasets identified differentially expressed and module genes, with their intersection as candidate genes. Core genes were identified through enrichment analysis and machine learning. Core gene expression was compared between control and osteosarcoma groups.
Zheng Li   +7 more
wiley   +1 more source

Identification of Crucial Genes Associated With MYCN‐Driven Neuroblastoma Based on Single‐Cell Analysis and Machine Learning

open access: yesCancer Medicine, Volume 14, Issue 13, July 2025.
By analyzing single‐cell transcriptomic data from 5 neuroblastoma patients with MYCN amplification and 7 patients without MYCN amplification (GSE21840), and applying machine learning approaches, we identified five candidate pathogenic genes potentially associated with MYCN amplification.
Jiasi Zhang   +8 more
wiley   +1 more source

Incidence, Outcomes and Risk Factors for Atrial Fibrillation in Patients With JAK2V617F‐Positive Myeloproliferative Neoplasms

open access: yesCancer Medicine, Volume 14, Issue 13, July 2025.
ABSTRACT Background The incidence, outcomes and risk factors for AF in the JAK2V617F‐positive MPN patients are still unknown. Methods The clinical profiles of patients with JAK2V617F‐positive MPN were retrospectively analyzed. Multivariable Cox regression analysis was performed to identify risk factors of AF, thereby developing a risk prediction model.
Guangshuai Teng   +16 more
wiley   +1 more source

A Nomogram Incorporating Intracranial Atherosclerosis Score for Predicting Early Neurological Deterioration in Minor Stroke Patients With Type 2 Diabetes Mellitus

open access: yesDiabetes, Metabolic Syndrome and Obesity
Jia Shang,1,2 Zehao Zhang,1 Shifang Ma,1 Hailong Peng,1 Lan Hou,1,3 Fan Yang,1 Pei Wang1,3 1Department of Neurology, Baoding No 1 Central Hospital, Baoding, People’s Republic of China; 2Graduate School of Hebei Medical University, Shijiazhuang,People’s ...
Shang J   +6 more
doaj  

Identification of Androgen Receptor as a Molecular Docking Target for Survival and Response to Metformin‐Induced Ferroptosis in Liver Cancer

open access: yesCancer Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background Hepatocellular Carcinoma (HCC) ranks among the most prevalent human cancers and stands as the third most common cause of death related to cancer globally. Current therapies for HCC include surgical resection, local ablation, chemoembolization, liver transplantation, and molecular‐targeted therapy. Only a small number of patients are
Bin Zhang   +7 more
wiley   +1 more source

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