Results 11 to 20 of about 13,542,190 (238)

Substance

open access: yes, 2023
The term “substance” has two main uses in philosophy. Both originate in what is arguably the most influential work of philosophy ever written, Aristotle’s Categories.
Ralph Weir (17169727)
core   +5 more sources

Regulatory Evolution of Neonicotinoid Insecticides as Plant Protection Active Substances in Europe

open access: yesAgrochemicals, 2023
Neonicotinoid (NN) insecticides derived from natural insecticide nicotine are EU chemical crop protection systemic active substances that are controversial regarding their toxicity and ecotoxicity, especially versus pollinators and birds.
Patrice A. Marchand
doaj   +1 more source

Basic substances under EC 1107/2009 phytochemical regulation: experience with non-biocide and food products as biorationals

open access: yesJournal of Plant Protection Research, 2016
Basic Substances are a newly effective category of Plant Protection Product under EC Regulation No 1107/2009. The first approved application of Equisetum arvense L.
Marchand Patrice A.
doaj   +1 more source

Neuromodulatory treatments for psychiatric disease: A comprehensive survey of the clinical trial landscape

open access: yesBrain Stimulation, 2021
Background: Numerous neuromodulatory therapies are currently under investigation or in clinical use for the treatment of psychiatric conditions.
Gavin J.B. Elias   +18 more
doaj   +1 more source

Scientific Opinion on the safety evaluation of the active substance iron (II) modified bentonite as oxygen absorber for use in active food contact materials [PDF]

open access: yesEFSA Journal, 2012
<p>This scientific opinion of EFSA deals with the safety evaluation of the active substance iron (II) modified bentonite (FCM Substance No 1003) intended to be incorporated in monolayer or multilayer packages or in sachets for absorbing oxygen from
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Biological screening of a unique drug library targeting MRGPRX2

open access: yesFrontiers in Immunology, 2022
BackgroundAllergic drug reaction or drug allergy is an immunologically mediated drug hypersensitivity reaction (DHR). G-protein coupled receptors (GPCRs) are common drug targets and communicate extracellular signals that initiate cellular responses ...
Fan Yang   +8 more
doaj   +1 more source

Unapproved clinical trials in Russia: exception or norm?

open access: yesBMC Medical Ethics, 2021
Background In modern Russia, any clinical investigation of a pharmaceutical for use in humans is subject to prior evaluation and approval by the Ministry of Health and its Central Ethics Committee.
Petr Talantov   +4 more
doaj   +1 more source

Photodegradation of Bexarotene and Its Implication for Cytotoxicity

open access: yesPharmaceutics, 2021
A detailed understanding of the stability of an active pharmaceutical ingredient and a pharmaceutical dosage form is essential for the drug-development process and for safe and effective use of medicines.
Agata Kryczyk-Poprawa   +8 more
doaj   +1 more source

Antimitotic action of cornin as a biologically active polypeptide. I. Biochemical properties of cornin [PDF]

open access: yes, 1965
We succeeded in the extraction of a substance from beef cornea and rabbit muscle, that markedly inhibits mitosis of sea urchin eggs. The substance extracted from beef cornea is non-dialysable and it can be separated into three fractions by DEAE-cellulose
Murakami, Tetuhide H., Nisida, Isamu
core   +1 more source

Methodology of the Development of a Topical Transdermal Fucoidan Delivery System

open access: yesРазработка и регистрация лекарственных средств, 2023
Introduction. Marine-derived polysaccharides are promising candidates for the development of innovative drugs. One of such compounds is the polysaccharide fucoidan from brown seaweeds, which shows anticoagulant and anti-inflammatory activity.
E. D. Obluchinskaya   +2 more
doaj   +1 more source

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