Methodology of the Development of a Topical Transdermal Fucoidan Delivery System
Introduction. Marine-derived polysaccharides are promising candidates for the development of innovative drugs. One of such compounds is the polysaccharide fucoidan from brown seaweeds, which shows anticoagulant and anti-inflammatory activity.
E. D. Obluchinskaya +2 more
doaj +1 more source
Psychometric properties of the Brief-COPE for the evaluation of coping strategies in the Chilean population [PDF]
The Brief-COPE is an abbreviated version of the COPE (Coping Orientation to Problems Experienced) Inventory, a self-report questionnaire developed to assess a broad range of coping responses. Currently, it is one of the best validated and most frequently
Alvear-Carrasco, Marcela +4 more
core +4 more sources
The Role of Early Maladaptive Schemas and Coping Strategies in Substance Dependency
Objective: The aim of this study was to evaluate the early maladaptive schemas and coping strategies of substance dependents. We hypothesized that substance dependents would have more maladaptive unhealthy schemas and would use less adaptive coping ...
Bikem Haciomeroglu +4 more
doaj +1 more source
Low prevalence of hepatitis C co-infection in recently HIV-infected minority men who have sex with men in Los Angeles: a cross-sectional study. [PDF]
BackgroundGeographic and sociodemographic characterization of hepatitis C virus (HCV) transmission amongst men who have sex with men (MSM) has been limited.
Bhattacharya, Debika +7 more
core +2 more sources
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
Category: Hindfoot; Sports Introduction/Purpose: Insertional and non-insertional Achilles tendinopathy (AT) are prevalent diseases in the active, working-age population.
Ruth Chimenti PT, PhD +9 more
doaj +1 more source
Targeting tachykinin receptors in neuroblastoma [PDF]
Neuroblastoma is the most common extracranial tumor in children. Despite aggressive multimodal treatment, high-risk neuroblastoma remains a clinical challenge with survival rates below 50%.
Althoff, Kristina +14 more
core +3 more sources
Background and Objective Oral tramadol, an atypical opioid approved in the United States (US) since 1995 and a Schedule IV controlled substance, has less abuse liability compared to Schedule II conventional opioids.
Harold Minkowitz +8 more
doaj +1 more source
Wild bee toxicity data for pesticide risk assessments [PDF]
Pollination services are vital for agriculture, food security and biodiversity. Although many insect species provide pollination services, honeybees are thought to be the major provider of this service to agriculture. However, the importance of wild bees
Lewis, Kathleen, Tzilivakis, John
core +2 more sources
The Regulatory Review Process in South Africa: Challenges and Opportunities for a New Improved System. [PDF]
BACKGROUND: The aims of this study were to assess the regulatory review process in South Africa from 2015 to 2017, identify the key milestones and timelines; evaluate the effectiveness of measures to ensure consistency, transparency, timeliness, and ...
M Cone +4 more
core +2 more sources

