Results 71 to 80 of about 14,087,183 (243)

Regulatory Compliance of Health Claims on Omega-3 Fatty Acid Food Supplements

Foods
Unlike the mandatory information that must be provided on a food supplement label, health claims are voluntary. This study assesses the regulatory compliance of omega-3 fatty acid (ω-3-FA) supplement label claims.
Jelena Banović Fuentes, Ivana Beara, Ljilja Torović   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The effectiveness of psychological interventions delivered by health professionals for adult cannabis use in community settings: a systematic review and meta-analysis

Frontiers in Psychiatry
IntroductionCannabis is one of the most widely used psychoactive substances and is associated with negative consequences affecting physical and mental health, cognition, quality of life, functional outcomes, employment, and interpersonal relationships ...
Sabrina Giguère, Sabrina Giguère, Stéphane Potvin, Stéphane Potvin, Mélissa Beaudoin, Mélissa Beaudoin, Xavier Wurtele Boudreau, Charles-Édouard Giguère, Alexandre Dumais, Alexandre Dumais, Alexandre Dumais   +10 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Other title: Kansas Substance Abuse Policy Board January 2009 Report

, 2009
Annual.; January 2009.; "Established by the Kansas Criminal Justice Coordinating Council."; "The Governor and the 2008 Legislature authorized the creation of the Substance Abuse Policy Board (SAPB) under the auspices of the Kansas Criminal Justice ...
Kansas Substance Abuse Policy Board.
core  

An example of International Drug Politics : The Development and Distribution of Substance Prevention Programs directed at Adolescents

, 2007
Many substance use prevention programs directed at adolescents exist that have been developed by researchers in the United States and are intended to be used in school settings.
Lilja, John, Hamilton, D, Larsson, Sam,, Giota, J, Hamilton, David, Larsson, Sam, Giota, Joanna,   +6 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Composition consisting of a dendrimer and an active substance [PDF]

, 1995
The invention relates to a composition consisting of a dendrimer provided with blocking agents and an active substance occluded in the dendrimer. According to the invention a blocking agent is a compound which is sterically of sufficient size, which ...
Brabander-van den Berg, de, E.M.M., Jansen, J.F.G.A., Meijer, E.W.   +2 more
core   +3 more sources