Results 11 to 20 of about 1,078,147 (263)

MicroRNA-24 in Cancer: A Double Side Medal With Opposite Properties

Frontiers in Oncology, 2020
MicroRNA-24 (miR-24) has been widely studied in a variety of human cancers, which plays different roles in specific type of cancers. In the present review, we summarized the recent surveys regarding the role of miR-24 in different human cancers.
Sumei Wang, Sumei Wang, Sumei Wang, Nayan Liu, Nayan Liu, Nayan Liu, Nayan Liu, Qing Tang, Qing Tang, Qing Tang, Honghao Sheng, Honghao Sheng, Honghao Sheng, Shunqin Long, Shunqin Long, Shunqin Long, Wanyin Wu, Wanyin Wu, Wanyin Wu   +18 more
doaj   +1 more source

Non-small-cell lung cancer: how to manage RET-positive disease

Drugs in Context, 2022
Targeted therapy has dramatically changed the history and outcomes of oncogene-addicted non-small-cell lung cancer (NSCLC). RET rearrangements are typically observed in about 1–2% of NSCLC, resulting in constitutive activation of downstream signalling ...
Elisa Andrini, Mirta Mosca, Linda Galvani, Francesca Sperandi, Biagio Ricciuti, Giulio Metro, Giuseppe Lamberti   +6 more
doaj   +1 more source

Non-small-cell lung cancer: how to manage EGFR-mutated disease

Drugs in Context, 2022
The treatment of non-small-cell lung cancer (NSCLC) harbouring EGFR mutations has witnessed some major breakthroughs in the last years. On the one hand, the recent advent of the third-generation tyrosine kinase inhibitor (TKI) osimertinib has reshaped ...
Federica Pecci, Luca Cantini, Giulio Metro, Biagio Ricciuti, Giuseppe Lamberti, Ammad Ahmad Farooqi, Rossana Berardi   +6 more
doaj   +1 more source

Non‐small cell lung cancer in China

Cancer Communications, 2022
In China, lung cancer is a primary cancer type with high incidence and mortality. Risk factors for lung cancer include tobacco use, family history, radiation exposure, and the presence of chronic lung diseases. Most early‐stage non‐small cell lung cancer
Peixin Chen, Yunhuan Liu, Yaokai Wen, Caicun Zhou   +3 more
doaj   +1 more source

Salivary cytokine panel indicative of non-small cell lung cancer. [PDF]

, 2018
Objective To develop a combinatorial panel of salivary cytokines that manifests the presence of non-small cell lung cancer (NSCLC) that will eventually improve prognosis by facilitating the early diagnosis and management of this common cancer. Methods We
Koizumi, Tomonobu, Shetty, Vivek, Yamaguchi, Masaki   +2 more
core   +3 more sources

Non-small-cell lung cancer: how to manage BRAF-mutated disease

Drugs in Context, 2023
BRAF mutations are reported in about 3–5% of non-small-cell lung cancer (NSCLC), almost exclusively in adenocarcinoma histology, and are classified into three different classes. The segmentation of BRAF mutations into V600 (class 1) and non-V600 (classes
Giorgia Guaitoli, Lodovica Zullo, Marcello Tiseo, Matthew Dankner, April AN Rose, Francesco Facchinetti   +5 more
doaj   +1 more source

Overexpression of the non-coding SOX2OT variants 4 and 7 in lung tumors suggests an oncogenic role in lung cancer [PDF]

, 2016
Despite the advances in cancer therapy, lung cancer still remains the most leading cause of cancer death worldwide. The long non-coding RNAs (lncRNAs) are recently introduced as novel regulators of human cancers. SOX2 overlapping transcript (SOX2OT) is a
Ghanei, M., Mowla, S.J., Saghaeian Jazi, M., Samaei, N.M., Shadmehr, M.B.   +4 more
core   +1 more source

Characteristics and outcome of patients with newly diagnosed advanced or metastatic lung cancer admitted to intensive care units (ICUs) [PDF]

, 2018
BACKGROUND: Although patients with advanced or metastatic lung cancer have poor prognosis, admission to the ICU for management of life-threatening complications has increased over the years.
A Steven, A-C Barbot, A-C Toffart, AK Adam, C Hamard, CA Reichner, CG Slatore, DV Schapira, E Azoulay, E Azoulay, E Biskup, F Vincent, FS Taccone, JI Salluh, JL Vincent, JR Gall Le, K Puxty, M Früh, M Garrouste-Orgeas, M Maltoni, M Soares, M Soares, M Soares, ME Charlson, MM Oken, MR Bonomi, P Zarogoulidis, R Fisher, RR Jennens, S Anisoglou, S Roques, T Cooksley, T Tanvetyanon, X Nan, Y Zerbib, Y-F Chen, YJ Kim   +36 more
core   +2 more sources

Deep segmentation networks predict survival of non-small cell lung cancer [PDF]

, 2019
Non-small-cell lung cancer (NSCLC) represents approximately 80-85% of lung cancer diagnoses and is the leading cause of cancer-related death worldwide. Recent studies indicate that image-based radiomics features from positron emission tomography-computed
Allen, Bryan, Baek, Stephen, Baek, Stephen, Buatti, John, Cabel, Katherine, Diehn, Maximilian, Gannon, Maggie, He, Yusen, Kim, Yusung, Loo, Billy, Plichta, Kristin, Seyedin, Steven, Smith, Brian, Sun, Zhiyu, Tong, Ling, Wu, Jia, Wu, Xiaodong   +16 more
core   +2 more sources

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells [PDF]

, 2016
Cancer stem cells (CSCs) play an important role in tumor initiation, progression, therapeutic failure and tumor relapse. In this study, we evaluated the efficacy of the thiazole derivative 3-methylcyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl ...
Buglioni, Simonetta, Carradori, Simone, DE LUCA, Teresa, De Maria, Ruggero, Del Bufalo, Donatella, Desideri, Marianna, DI MARTILE, Marta, Eramo, Adriana, Gabellini, Chiara, Mai, Antonello, Milella, MICHELE STANISLAW, Rotili, Dante, Secci, Daniela, Sette, Giovanni, Trisciuoglio, Daniela   +14 more
core   +8 more sources