Results 181 to 190 of about 1,404,058 (313)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Non-viral gene delivery for non-small cell lung cancer. [PDF]

Ann Transl Med
Fung V, Gill NA, Andersen S, Fenton OS.
europepmc   +1 more source

Durvalumab after Chemoradiotherapy in Stage III Non–Small‐Cell Lung Cancer

New England Journal of Medicine, 2017
S. Antonia, A. Villegas, D. Daniel, D. Vicente, S. Murakami, R. Hui, T. Yokoi, A. Chiappori, K. Lee, M. de Wit, B. Cho, M. Bourhaba, X. Quantin, T. Tokito, T. Mekhail, D. Planchard, Young‐Chul Kim, C. Karapetis, S. Hiret, G. Ostoros, K. Kubota, J. Gray, L. Paz-Ares, J. de Castro Carpeño, C. Wadsworth, G. Melillo, Haiyi Jiang, Yi-fan Huang, P. Dennis, M. Özgüroğlu   +29 more
semanticscholar   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Cemiplimab in Japanese patients with advanced non-small cell lung cancer. [PDF]

Jpn J Clin Oncol
Sato Y, Tani Y, Ishii H, Katakura S, Oki M, Watanabe Y, Yokoyama T, Naoki K, Pouliot JF, Kaul M, Paccaly A, Visich JE, Kim E, Mani J, Li Y, Lowy I, Seebach F, Mathias M, Ikeda S.   +18 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Angiogenesis and Non Small Cell Lung Cancer

Balkan Journal of Medical Genetics, 2008
Metodieva S
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

N1‐methylpseudouridine modification level correlates with protein expression, immunogenicity, and stability of mRNA

MedComm
Shaoyi Chen, Zheng Liu, Jingsheng Cai, Haoran Li, Mantang Qiu   +4 more
doaj   +1 more source

Understanding Non-Small-Cell Lung Cancer: Biology, Therapeutics and Drug Resistance. [PDF]

Biomedicines
Ahluwalia P, Kolhe R, Rojiani M.
europepmc   +1 more source