Results 131 to 140 of about 775,156 (335)

Moldova’s 'wannabe democracy' is worth rescuing. CEPS Policy Brief No. 185, 23 April 2009 [PDF]

open access: yes, 2009
The consequences of the post-electoral impasse in which Moldova finds itself after the parliamentary elections on 5 April 2009 are immense for the EU’s relations with Moldova and for the success of its European Neighbourhood Policy (ENP) and Eastern ...
Dura, George, Gnedina, Elena.
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Are Girls Neko or Shōjo? Cross-Lingual Alignment of Non-Isomorphic Embeddings with Iterative Normalization [PDF]

open access: gold, 2019
Mozhi Zhang   +4 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Robust adaptive non‐linear alignment algorithm for SINS/DVL integrated navigation system based on variational Bayesian

open access: yesIET Science, Measurement & Technology
The problem of dynamic attitude alignment for strapdown inertial navigation system (SINS) and Doppler velocity log (DVL) integrated navigation has become a research hotspot. Underwater complex environment makes DVL output vulnerable to non‐Gaussian noise
Bing Zhu   +5 more
doaj   +1 more source

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