Results 111 to 120 of about 8,104,442 (314)

Factors influencing the success of business-IT alignment : a study of South African firms

, 2010
Includes abstract.Includes bibliographical references (leaves 124-138).This study investigated the factors influencing the success of business-IT alignment in South African firms while taking into consideration the coverage of the requisite dimensions ...
Onumajuru, Paulinus Uche
core  

Tanzania, the Non-Aligned Movement and Non Alignment [PDF]

, 2021
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Bootstrapping word alignment via word packing [PDF]

, 2007
We introduce a simple method to pack words for statistical word alignment. Our goal is to simplify the task of automatic word alignment by packing several consecutive words together when we believe they correspond to a single word in the opposite ...
Stroppa, Nicolas, Way, Andy, Ma, Yanjun
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

LEADERSHIP AND STRATEGIC ALIGNMENT IN CONSTRUCTION

, 2010
Construction management and engineering is generally thought of as a purely technical part of construction management consisting of bar charts, scheduling, estimates and bidding. While these tools may guide a company to construct a project, the
Acacio, PhD, Alexis A.
core  

CNCA aligns small annotated genomes

BMC Bioinformatics
Background To explore the evolutionary history of sequences, a sequence alignment is a first and necessary step, and its quality is crucial. In the context of the study of the proximal origins of SARS-CoV-2 coronavirus, we wanted to construct an ...
Jean-Noël Lorenzi, François Graner, Virginie Courtier-Orgogozo, Guillaume Achaz   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Sequence alignment, mutual information, and dissimilarity measures for constructing phylogenies

, 2011
Background: Existing sequence alignment algorithms use heuristic scoring schemes based on biological expertise, which cannot be used as objective distance metrics.
Penner, Orion, Grassberger, Peter, Maya Paczuski, Paczuski Maya, Peter Grassberger, Orion Penner, Penner Orion, Grassberger Peter, Paczuski, Maya   +8 more
core   +1 more source