Results 131 to 140 of about 8,104,442 (314)

All_Lophiobagrus-alignment

open access: yes, 2018
Alignment of RADseq data for Lophiobagrus cyclurus and Lophiobagrus ...
Julia J. Day (41547)   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Robust adaptive non‐linear alignment algorithm for SINS/DVL integrated navigation system based on variational Bayesian

open access: yesIET Science, Measurement & Technology
The problem of dynamic attitude alignment for strapdown inertial navigation system (SINS) and Doppler velocity log (DVL) integrated navigation has become a research hotspot. Underwater complex environment makes DVL output vulnerable to non‐Gaussian noise
Bing Zhu   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Time Interference Alignment via Delay Offset for Long Delay Networks

open access: yes, 2011
The potential of Time Interference Alignment is investigated in this work, with particular reference to the attainable degrees of freedom. The K-user interference channel is considered, in which transmitters and receivers are placed randomly in a ...
Francisco Lázaro Blasco   +7 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Strategic alignment: a performance tool (an empirical study of SMEs). [PDF]

open access: yes
The purpose of this research is to investigate whether the alignment of IT with the strategy (particularly the partnership strategy or cooperation practice) and organizational structure of an SME could have a decisive influence on its performance.
Kalika, Michel, Jouirou, Nihel
core  

Multi-word expression-sensitive word alignment [PDF]

open access: yes, 2010
This paper presents a new word alignment method which incorporates knowledge about Bilingual Multi-Word Expressions (BMWEs). Our method of word alignment first extracts such BMWEs in a bidirectional way for a given corpus and then starts conventional ...
Maldonado Guerra, Alfredo   +3 more
core  

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