Results 131 to 140 of about 12,495,287 (348)

PicXAA-R: Efficient structural alignment of multiple RNA sequences using a greedy approach

open access: yesBMC Bioinformatics, 2011
Background Accurate and efficient structural alignment of non-coding RNAs (ncRNAs) has grasped more and more attentions as recent studies unveiled the significance of ncRNAs in living organisms.
Yoon Byung-Jun   +1 more
doaj   +1 more source

17 July 2009 Jakarta bombing: the aftermath and longer-term implications [PDF]

open access: yes, 2009
Although the carnage in Indonesia was not as great or as bloody as in 2002, 2003 or 2005, the political lessons to be learned in the immediate aftermath of the July 17 2009 bombing are not to be neglected.
Majid, Munir
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Robust adaptive non‐linear alignment algorithm for SINS/DVL integrated navigation system based on variational Bayesian

open access: yesIET Science, Measurement & Technology
The problem of dynamic attitude alignment for strapdown inertial navigation system (SINS) and Doppler velocity log (DVL) integrated navigation has become a research hotspot. Underwater complex environment makes DVL output vulnerable to non‐Gaussian noise
Bing Zhu   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy