Results 121 to 130 of about 12,495,287 (348)

CNCA aligns small annotated genomes

BMC Bioinformatics
Background To explore the evolutionary history of sequences, a sequence alignment is a first and necessary step, and its quality is crucial. In the context of the study of the proximal origins of SARS-CoV-2 coronavirus, we wanted to construct an ...
Jean-Noël Lorenzi, François Graner, Virginie Courtier-Orgogozo, Guillaume Achaz   +3 more
doaj   +1 more source

First results from the CERN Axion Solar Telescope (CAST)

, 2004
Hypothetical axion-like particles with a two-photon interaction would be produced in the Sun by the Primakoff process. In a laboratory magnetic field (``axion helioscope'') they would be transformed into X-rays with energies of a few keV.
A. Belov, A. Liolios, A. Ljubičić, A. Morales, A. Nikolaidis, A. Ortiz, A. Placci, B. Beltrán, B. Lakić, C. Eleftheriadis, C. Lasseur, D. Autiero, D. H. H. Hoffmann, D. Kang, D. W. Miller, E. Chesi, E. Ferrer, F. H. Heinsius, F. T. Avignone, G. Fanourakis, G. Lutz, G. Luzón, G. Raffelt, H. Bräuninger, H. Farach, H. Fischer, H. Riege, I. G. Irastorza, I. Giomataris, I. Savvidis, J. Altmann, J. D. Vieira, J. Englhauser, J. Franz, J. I. Collar, J. Jacoby, J. M. Carmona, J. Morales, J. Ruz, J. Villar, K. Barth, K. Barth, K. Kousouris, K. Königsmann, K. Zachariadou, K. Zioutas, L. Di Lella, L. Stewart, L. Walckiers, M. D. Hasinoff, M. Davenport, M. Krčmar, M. Kuster, M. L. Sarsa, M. Mutterer, N. Goloubev, P. Friedrich, P. Serpico, R. Creswick, R. Kotthaus, S. Andriamonje, S. Aune, S. Cebrián, S. Gninenko, T. Dafni, T. Geralis, T. Papaevangelou, V. Arsov, W. Serber, Y. Semertzidis   +69 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Hundred Years Since Yugoslavia’s Birth: Lesson on Nationalism, Balkanization, and Religion in Europe’s Periphery

, 2019
In 2018, historians were marking the one hundredth anniversary of the foundation of a nation-state in southeastern Europe remembered as Yugoslavia–the country of Southern Slavs.
Perica, Vjekoslav
core  

Turkey's global strategy: Turkey and the United States [PDF]

, 2011
The recent evolution of US-Turkish relations highlights broader challenges of the transition from American unipolarity to a still inceptive ‘multipolar world’.
Alessandri, Emiliano
core  

New LHC Benchmarks for the CP-conserving Two-Higgs-Doublet Model

, 2015
We introduce a strategy to study the parameter space of the general, CP-conserving, two-Higgs-doublet Model (2HDM) with a softly broken Z_2-symmetry by means of a new "hybrid" basis.
Haber, Howard E., Stal, Oscar
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Principal Flow Patterns across renewable electricity networks

, 2018
Using Principal Component Analysis (PCA), the nodal injection and line flow patterns in a network model of a future highly renewable European electricity system are investigated. It is shown that the number of principal components needed to describe 95$\%
Brown, Tom, Greiner, Martin, Hofmann, Fabian, Hörsch, Jonas, Schramm, Stefan, Schäfer, Mirko   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source