Results 131 to 140 of about 24,186,788 (290)

Transmission of Non-B HIV Subtypes in the United Kingdom Is Increasingly Driven by Large Non-Heterosexual Transmission Clusters [PDF]

, 2016
BACKGROUND: The United Kingdom human immunodeficiency virus (HIV) epidemic was historically dominated by HIV subtype B transmission among men who have sex with men (MSM).
Dunn, D, Lycett, SJ, Hodcroft, EB, Fearnhill, E, Leigh Brown, AJ, Ragonnet-Cronin, M, Delpech, V, United Kingdom HIV Drug Resistance Database, Hué, S, Brown, AE   +9 more
core  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Analysis of Diffuse Large B Cell Lymphoma using Immunohistochemistry to Identify Double Expressor Diffuse Large B Cell Lymphoma among Germinal Centre and Non Germinal Centre B Cell Subtypes

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Background: Diffuse large B cell lymphoma (DLBCL) within non-Hodgkin lymphoma has several morphologic and clinicopathologic variants. DLBCL has two prognostically important subtypes, germinal center B cell (GCB) and nongerminal center (Non-GCB) with the ...
E R Jyothi Rani, Jasmin Scaria, P P Sathi   +2 more
doaj   +1 more source

Recurrence-Free Survival in Expression Subtypes.

, 2013
Kaplan-Meier plots and Log-Rank Test p-values comparing recurrence-free survival times in all expression subtypes (A), HPV+ vs. HPV− subjects (B), all expression subtypes in HPV− subjects (C), and AT vs. non-AT in HPV− subjects (D).
Matthew D. Wilkerson (165493), Ni Zhao (165503), Leigh B. Thorne (165521), D. Neil Hayes (165551), Mei Kim Ang (381290), Michele C. Hayward (165508), Fred A. Wright (202146), Xiaoying Yin (165499), Andrew F. Olshan (227311), Ashley H. Salazar (381291), Trevor Hackman (381296), Katherine A. Hoadley (240350), Scott H. Randell (165539), Christopher R. Cabanski (165505), Ying Du (42066), William D. Funkhouser (381297), Mark C. Weissler (227312), Adam M. Zanation (381295), Charles G. Sailey (381293), Vonn Walter (165501), Carol G. Shores (381299), Karen Fritchie (381292), Kenneth L. Muldrew (381298), William W. Shockley (381294)   +23 more
core   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

in cell of origin subtypes of Diffuse Large B Cell Lymphoma as defined by the Hans algorithm

, 2018
The Grupo Español de Linfomas y Trasplantes de Médula Ósea International Prognostic Index (GELTAMO-IPI) stratifies four risk groups in diffuse large B cell lymphoma (DLBCL) patients treated with immunochaemotherapy: low (LR), low-intermediate (LIR), high-
González de Villambrosia, Sonia, Silvana Novelli, María J. Rodriguez Salazar, García, Olga, Anna Monter‐Rovira, Córdoba, Raul, Salar, Antonio, Fernández, Rubén, Raquel De Oña, Carlos Montalbán, Antonio Díaz‐López, Novelli, Silvana, GELTAMO-IPI Project Investigators, Montalbán, Carlos, Mariana Bastos, Bento, Leyre, López Guillermo, Armando, Baile, Mónica, Rodríguez, José, Queizan, José A, José Rodríguez, Sanchez, José M, Domínguez, Juan F, Rubén Fernández, Rodriguez Salazar, María J, Sonia González de Villambrosia, Victor Abraira, Mónica Baile, Leyre Bento, Juan F. García, Juan F. Domínguez, De Oña, Raquel, Barranco, Gilberto, Olga García, Díaz-López, Antonio, Sancho, Juan M, Armando López Guillermo, Antonio Salar, Gutiérrez, Antonio, Juan M. Sancho, José A. Queizan, Arquero, Teresa, Monter-Rovira, Anna, Abraira, Victor, Alejandro Martín, Martín, Alejandro, José M. Sanchez, García, Juan F, Bastos, Mariana, Antonio Gutiérrez, Teresa Arquero, Raul Córdoba, Gilberto Barranco   +52 more
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source