Results 41 to 50 of about 24,186,788 (290)

Biomarker characterization of clinical subtypes of Parkinson Disease

npj Parkinson's Disease, 2022
The biological underpinnings of the PD clusters remain unknown as the existing PD clusters lacks biomarker characterization. We try to identify clinical subtypes of Parkinson Disease (PD) in an Asian cohort and characterize them by comparing clinical ...
Xiao Deng, Seyed Ehsan Saffari, Nan Liu, Bin Xiao, John Carson Allen, Samuel Yong Ern Ng, Nicole Chia, Yi Jayne Tan, Xinyi Choi, Dede Liana Heng, Yew-long Lo, Zheyu Xu, Kay-Yaw Tay, Wing-Lok Au, Adeline Ng, Eng-King Tan, Louis C. S. Tan   +16 more
doaj   +1 more source

Increasing Frequency and Transmission of HIV-1 Non-B Subtypes among Men Who Have Sex with Men in the Swiss HIV Cohort Study.

, 2022
BACKGROUND In Switzerland, HIV-1 transmission among men who have sex with men (MSM) has been dominated by subtype B, whilst non-B subtypes are commonly attributed to infections acquired abroad among heterosexuals.
Yerly, Sabine, Günthard, Huldrych F, Kouyos, Roger D, Nguyen, Huyen, Furrer, Hansjakob, Chaudron, Sandra E, Stöckle, Marcel, Hirsch, Hans H, Ramette, Alban Nicolas, Kusejko, Katharina, Perreau, Matthieu, Vernazza, Pietro, Ballouz, Tala, Duran Ramirez, Jessy J, Huber, Michael, Cavassini, Matthias, Bernasconi, Enos   +16 more
core   +1 more source

Cerebrospinal fluid viral load and intrathecal immune activation in individuals infected with different HIV-1 genetic subtypes. [PDF]

PLoS ONE, 2008
HIV-1 exhibits a high degree of genetic diversity and is presently divided into 3 distinct HIV-1 genetic groups designated major (M), non-M/non-O (N) and outlier (O).
Sahra Abdulle, Lars Hagberg, Bo Svennerholm, Dietmar Fuchs, Magnus Gisslén   +4 more
doaj   +1 more source

Cell of Origin Based on Hans’ Algorithm as Prognostic Factor in Diffuse Large B-Cell Lymphoma: A Clinicopathologic and Survival Study

Asian Pacific Journal of Cancer Care, 2022
Background: Diffuse Large B-Cell Lymphoma (DLBCL) has been classified based on Cell of Origin (COO) into Germinal Center B-cell (GCB) and Non-Germinal Center B-cell (Non-GCB).
Wiwiek Probowati, Ibnu Purwanto, Nungki Anggorowati, Syahru Agung Setiawan, Miraz Radhea Bagaskoro, Nugira Dinantia, Johan Kurnianda, Kartika Widayati Taroeno-Hariadi, Susanna Hilda Hutajulu, Mardiah Suci Hardianti   +9 more
doaj   +1 more source

Identification of Non‐B Human Immunodeficiency Virus Type 1 Subtypes in Rural Georgia [PDF]

The Journal of Infectious Diseases, 2001
As part of an ongoing molecular epidemiological investigation of human immunodeficiency virus type 1 (HIV-1) in rural Georgia, the 5' half of reverse transcriptase (RT) genotypes from 30 patients was sequenced and phylogenetically analyzed. Two patients, GA132 and GA169, were infected with pol sequences of non-B subtype origin that were found to ...
C, Womack, W, Roth, C, Newman, J P, Rissing, R, Lovell, D, Haburchak, M, Essex, V C, Bond   +7 more
openaire   +2 more sources

Aberrant Activation of NF-κB Signalling in Aggressive Lymphoid Malignancies

Cells, 2018
Lymphoid malignancies frequently harbor genetic mutations leading to aberrant activation of nuclear factor-κB (NF-κB) signaling; in normal cells, this pathway has important roles in the control of cell growth, survival, stress responses, and ...
Ruth Kennedy, Ulf Klein
doaj   +1 more source

Comparable long-term efficacy of Lopinavir/Ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. [PDF]

PLoS ONE, 2014
BACKGROUND: Analysis of potentially different impact of Lopinavir/Ritonavir (LPV/r) on non-B subtypes is confounded by dissimilarities in the conditions existing in different countries.
Zehava Grossman, Jonathan M Schapiro, Itzchak Levy, Daniel Elbirt, Michal Chowers, Klaris Riesenberg, Karen Olstein-Pops, Eduardo Shahar, Valery Istomin, Ilan Asher, Bat-Sheva Gottessman, Yonat Shemer, Hila Elinav, Gamal Hassoun, Shira Rosenberg, Diana Averbuch, Keren Machleb-Guri, Zipi Kra-Oz, Sara Radian-Sade, Hagit Rudich, Daniela Ram, Shlomo Maayan, Nancy Agmon-Levin, Zev Sthoeger   +23 more
doaj   +1 more source

Rising prevalence of non-B HIV-1 subtypes in North Carolina and evidence for local onward transmission. [PDF]

, 2017
HIV-1 diversity is increasing in North American and European cohorts which may have public health implications. However, little is known about non-B subtype diversity in the southern United States, despite the region being the epicenter of the nation's ...
Ann M. Dennis, William C. Miller, Emily Learner, Stephane Hué, Learner, Emily, Sebastian, Joseph, Joseph Sebastian, Dennis, Ann M, Hué, Stephane, Eron, Joseph J, Miller, William C, Joseph J. Eron   +11 more
core   +1 more source

HIV subtype, epidemiological and mutational correlations in patients from Paraná, Brazil

Brazilian Journal of Infectious Diseases
OBJECTIVE: Analyze patients with HIV infection from Curitiba, Paraná, their epidemiological characteristics and HIV RAM. METHODS: Patients regularly followed in an ID Clinic had their medical data evaluated and cases of virological failure were analyzed ...
Monica Maria Gomes da Silva, Flavio Queiroz Telles, Clovis Arns da Cunha, Frank S Rhame   +3 more
doaj   +1 more source

Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs

Viruses, 2010
Despite the fact that over 90% of HIV-1 infected people worldwide harbor non‑subtype B variants of HIV-1, knowledge of resistance mutations in non-B HIV-1 and their clinical relevance is limited.
Bluma G. Brenner, Mark A. Wainberg
doaj   +1 more source